Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …

The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …

The 'microbiota-gut-brain axis' plays a fundamental role in maintaining host homeostasis,
and different immune, hormonal, and neuronal signals participate to this interkingdom …

Background & Aims The existence of postinfection irritable bowel syndrome (PI-IBS) has
been substantiated by epidemiology studies conducted in diverse geographic and clinical …

While bidirectional brain–gut interactions are well known mechanisms for the regulation of
gut function in both healthy and diseased states, a role of the enteric flora—including both …

Background: IBS affects 5–11% of the population of most countries. Prevalence peaks in the
third and fourth decades, with a female predominance. Aim: To provide a guide for the …

Approximately 1 in ten patients with irritable bowel syndrome (IBS) believe their IBS began
with an infectious illness. Prospective studies have shown that 3% to 36% of enteric …

Irritable bowel syndrome (IBS) is a chronic functional disorder that affects the gastrointestinal
tract. Details regarding the pathogenesis of IBS remain largely unknown, though the …