Experimental and computational thermochemical study of benzofuran, benzothiophene and indole derivatives

F Ramos, H Flores, A Rojas… - the Journal of Chemical …, 2016 - Elsevier
The standard enthalpies of formation of benzofuran-, indole-, and benzothiophene-2-
carboxylic acids, and 2-acetylbenzofuran in the condensed phase were measured at T …

Benzo (B) thiophene-2-carboxylic acid: Calcium uptake and cyclic AMP production in isolated bone cells

JC Robin, MJ Brown, N Weinfeld, RM Dziak - Calcified tissue international, 1984 - Springer
The purpose of the present study was to investigate the mechanism of action on bone of
Benzo (B) Thiophene-2-Carboxylic Acid (BL-5583). BL-5583, at a dose range of 0.01–100 …

Effects of thionapthene 2-carboxylic acid and related compounds on bone resorption in organ culture

LG Raisz, C Alander, C Onkelinx, GA Rodan - Calcified tissue international, 1985 - Springer
We have compared the effects of thiophene 2-carboxylic acid (TCA) and a number of sulfur-
and nitrogen-containing analogs for their ability to inhibit bone resorption in organ cultures …

Studies on osteoporosis. V. Comparison of methods of evaluation of osteoporosis and study of chromosome changes induced by neutron activation.

JC Robin, SR Sirianni, DA Pragay, JL Ambrus - Journal of Medicine, 1981 - europepmc.org
In vivo activation analysis was compared with ashing and atomic absorption
spectrophotometry for the determination of total skeletal calcium content in mice. The results …

Medicinal Chemistry Opportunities in Bone Metabolism and Osteoporosis

MA Hayward, TJ Caggiano - Annual Reports in Medicinal Chemistry, 1987 - Elsevier
Publisher Summary Recent research has aided in a substantial increase in the knowledge
of basic bone metabolism. Bone is a dynamic tissue that continuously undergoes …

The Effect of 2-Thiophenecarboxylic Acid on Growth Plate in the HEBP Induced Rachitic Rats

T Shimauchi, M Eguchi, H Kawamura… - Orthopedics & …, 1987 - jstage.jst.go.jp
Thiophenecarboxylic acid, a hypoglycemic and antilipolitic agent first described by Fang,
was subsequently shown to produce hypocalcemic and hypophosphatemic effects in rats …

Calcium Antagonist Diltiazem Inhibits Calcification Enhanced by 2-Thiophenecarboxylic Acid in Growth Cartilage of Rat in 1-Hydroxyethylidene-1, 1-Bisphosphonate …

T Shimauchi, M Eguchi, F Wada, K Shibata… - Orthopedics & …, 1987 - jstage.jst.go.jp
2-Thiophenecarboxylic acid was shown to produce hypocalcemic and hypoglycemic effects
in rats by Lloyd (1969). We reported previously that 2-TCA enhanced calcification in growth …

HEBP (EHDP) くる病ラットの成長軟骨における2‐Thiophenecarboxylic acid の効果

島内卓, 江口正雄, 川村秀哉, 柴田堅一郎… - 整形外科と災害 …, 1987 - jlc.jst.go.jp
HEBP(EHDP)く る病 ラ ッ トの 成 長 軟 骨 に お け る 2-Thiophenecarboxylic Acidの 効 T Page
1 1088 整 形 外 科 と 災 害 外 科 35:(4)1088∼1093,1987. HEBP(EHDP)く る病 ラ ッ トの 成 長 …

1‐Hydroxyethylidene‐1, 1‐bisphosphonic acid (HEBP) くる病ラットの成長軟骨に対する2‐Thiophenecarboxylic acid (TCA) の石灰化促進効果におよぼすカルシウムきっ抗 …

島内卓, 江口正雄, 和田文夫, 柴田堅一郎… - 整形外科と災害 …, 1987 - jlc.jst.go.jp
2-Thiophenecarboxylic acid was shown to produce hypocalcemic and hypoglycemic effects
in rats by Lloyd (1969). We reported previously that 2-TCA enhanced calcification in growth …