Baking soda and vinegar have been used as home remedies for generations and today we
are only a mouse-click away from claims that baking soda, lemon juice, and apple cider …

The epithelial Na+ channel (ENaC) and the acid-sensing ion channels (ASICs) form
subfamilies within the ENaC/degenerin family of Na+ channels. ENaC mediates …

Acid-sensing ion channels (ASICs) are ligand-gated ion channels that are exquisitely
sensitive to extracellular protons and can sense transient as well as sustained acidification …

Background Acid-sensing ion channels (ASICs) are a group of amiloride-sensitive ligand-
gated ion channels belonging to the family of degenerin/epithelial sodium channels. ASICs …

Since their molecular cloning in the late 90's, Acid-Sensing Ion Channels (ASICs) have been
shown to be involved in many aspects of nociception, both in peripheral and central …

Acid-sensing ion channels (ASICs) are proton-gated members of the epithelial sodium
channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed throughout …

Acid‐sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC) are both
members of the ENaC/degenerin family of amiloride‐sensitive Na+ channels. ASICs act as …

Research findings over the past two decades have supported a link between sleep states
and synaptic plasticity. Numerous mechanistic hypotheses have been put forth to explain …

Tissue acidification is associated with a variety of disease states, and acid-sensing ion
channels (ASICs) that can sense changes in pH have gained traction as possible …

Abstract Development of the pharmacology of Acid-Sensing Ion Channels (ASICs) has
become a key challenge to study their structure, their molecular and cellular functions and …