Modular Synthetic Platform to Tailor Therapeutic-Specific Delivery in Injectable Hydrogels
Injectable thermoresponsive hydrogels (thermogels), valued for their conformability and
minimal invasiveness, are increasingly used as in situ forming implants for drug delivery and …
minimal invasiveness, are increasingly used as in situ forming implants for drug delivery and …
Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma
J Sun, Y Lei, Z Dai, X Liu, T Huang, J Wu… - … applied materials & …, 2017 - ACS Publications
A novel layered double hydroxide (LDH) nanoparticle/thermogel composite drug delivery
system (DDS) for sustained release of brimonidine (Bri) has been designed, prepared, and …
system (DDS) for sustained release of brimonidine (Bri) has been designed, prepared, and …
Gold nanoparticle-functionalized reverse thermal gel for tissue engineering applications
Utilizing polymers in cardiac tissue engineering holds promise for restoring function to the
heart following myocardial infarction, which is associated with grave morbidity and mortality …
heart following myocardial infarction, which is associated with grave morbidity and mortality …
Injectable carbon nanotube-functionalized reverse thermal gel promotes cardiomyocytes survival and maturation
The ability of the adult heart to regenerate cardiomyocytes (CMs) lost after injury is limited,
generating interest in developing efficient cell-based transplantation therapies. Rigid carbon …
generating interest in developing efficient cell-based transplantation therapies. Rigid carbon …
Injectable polymeric delivery system for spatiotemporal and sequential release of therapeutic proteins to promote therapeutic angiogenesis and reduce inflammation
AJ Rocker, DJ Lee, R Shandas… - ACS biomaterials science …, 2020 - ACS Publications
Myocardial infarction (MI) causes cardiac cell death, induces persistent inflammatory
responses, and generates harmful pathological remodeling, which leads to heart failure …
responses, and generates harmful pathological remodeling, which leads to heart failure …
Hereditary Optic Neuropathies: A Systematic Review on the Interplay between Biomaterials and Induced Pluripotent Stem Cells
M Ladero, JA Reche-Sainz, ME Gallardo - Bioengineering, 2024 - mdpi.com
Hereditary optic neuropathies (HONs) such as dominant optic atrophy (DOA) and Leber
Hereditary Optic Neuropathy (LHON) are mitochondrial diseases characterized by a …
Hereditary Optic Neuropathy (LHON) are mitochondrial diseases characterized by a …
Inputs of macromolecular engineering in the design of injectable hydrogels based on synthetic thermoresponsive polymers
V Pertici, T Trimaille, D Gigmes - Macromolecules, 2020 - ACS Publications
Injectable hydrogels have received high attention over the last decades in drug delivery and
tissue engineering as they allow minimal invasive procedures. Among them …
tissue engineering as they allow minimal invasive procedures. Among them …
An injectable sulfonated reversible thermal gel for therapeutic angiogenesis to protect cardiac function after a myocardial infarction
DJ Lee, MA Cavasin, AJ Rocker, DE Soranno… - Journal of biological …, 2019 - Springer
Background Cardiovascular disease and myocardial infarction are associated with high
mortality and morbidity and a more effective treatment remains a major clinical need. The …
mortality and morbidity and a more effective treatment remains a major clinical need. The …
Polybenzyl glutamate biocompatible scaffold promotes the efficiency of retinal differentiation toward retinal ganglion cell lineage from human-induced pluripotent stem …
Optic neuropathy is one of the leading causes of irreversible blindness caused by retinal
ganglion cell (RGC) degeneration. The development of induced pluripotent stem cell (iPSC) …
ganglion cell (RGC) degeneration. The development of induced pluripotent stem cell (iPSC) …
Injectable neurotrophic factor delivery system supporting retinal ganglion cell survival and regeneration following optic nerve crush
MR Laughter, JR Bardill, DA Ammar… - ACS biomaterials …, 2018 - ACS Publications
In general, neurons belonging to the central nervous system (CNS), such as retinal ganglion
cells (RGCs), do not regenerate. Due to this, strategies have emerged aimed at protecting …
cells (RGCs), do not regenerate. Due to this, strategies have emerged aimed at protecting …