Up to 50% of cancer patients suffer from a progressive atrophy of adipose tissue and
skeletal muscle, called cachexia, resulting in weight loss, a reduced quality of life, and a …

White adipose tissue is recognized as a dynamic endocrine organ able to produce and
release several bioactive polypeptides known as adipokines. Obesity is defined as an …

White adipose tissue (WAT) is now recognized as a major endocrine and secretory organ,
releasing a wide range of protein factors and signals termed adipokines–in addition to fatty …

With the growing prevalence of obesity, scientific interest in the biology of adipose tissue has
been extended to the secretory products of adipocytes, since they are increasingly shown to …

This paper considers the role of putative adipokines that might be involved in the enhanced
inflammatory response of human adipose tissue seen in obesity. Inflammatory adipokines [IL …

Abstract Zinc α2-glycoprotein (ZAG) is a protein of interest because of its ability to play many
important functions in the human body, including fertilization and lipid mobilization. After the …

Abstract The human Simpson-Golabi-Behmel syndrome (SGBS) preadipocyte cell strain
provides a unique and useful tool for studies of human adipocyte biology. The cells originate …

Seminal plasma contains a large protein component which has been implicated in the
function, transit and survival of spermatozoa within the female reproductive tract. However …

Macrophage inhibitory cytokine-1 (MIC-1), a divergent member of the TGF-β superfamily, is
involved in the control of multiple cellular processes and mediates cachexia through the …

Cancer cachexia is a multifactorial syndrome that is characterised by a loss of skeletal
muscle mass, is commonly associated with adipose tissue wasting and malaise, and …