Appreciating the role of cell shape changes in the mechanobiology of epithelial tissues

M Luciano, M Versaevel, E Vercruysse, A Procès… - Biophysics …, 2022 - pubs.aip.org
The wide range of epithelial cell shapes reveals the complexity and diversity of the
intracellular mechanisms that serve to construct their morphology and regulate their …

Shining a light on RhoA: Optical control of cell contractility

S Chandrasekar, JR Beach, PW Oakes - The International Journal of …, 2023 - Elsevier
In addition to biochemical and electrochemical signaling, cells also rely extensively on
mechanical signaling to regulate their behavior. While a number of tools have been adapted …

[HTML][HTML] Tropoelastin improves adhesion and migration of intra-articular injected infrapatellar fat pad MSCs and reduces osteoarthritis progression

J Yang, X Wang, Y Fan, X Song, J Wu, Z Fu, T Li… - Bioactive materials, 2022 - Elsevier
Tropoelastin improves adhesion and migration of intra-articular injected infrapatellar fat pad
MSCs and reduces osteoarthritis progression - ScienceDirect Skip to main contentSkip to …

The integrin pathway partially mediates stretch-induced deficits in primary rat microglia

MC Shaughness, N Pierron, AN Smith… - Molecular …, 2023 - Springer
Stretch-injured microglia display significantly altered morphology, function and inflammatory-
associated gene expression when cultured on a synthetic fibronectin substrate. However …

Ras-mediated homeostatic control of front-back signaling dictates cell polarity

Y Lin, DS Pal, P Banerjee, T Banerjee, G Qin, Y Deng… - bioRxiv, 2023 - biorxiv.org
Studies in the model systems, Dictyostelium amoebae and HL-60 neutrophils, have shown
that local Ras activity directly regulates cell motility or polarity. Localized Ras activation on …

Assessment of the effects of stretch-injury on primary rat microglia

M Shaughness, K Byrnes - Molecular Neurobiology, 2021 - Springer
Mechanical stretch-injury is a prominent force involved in the etiology of traumatic brain
injury (TBI). It is known to directly cause damage and dysfunction in neurons, astrocytes, and …

Interpretable Phenotypic Profiling of 3D Cellular Morphodynamics

M De Vries, R Naidoo, O Fourkioti, LG Dent… - … Conference on Medical …, 2024 - Springer
The dynamic 3D shape of a cell acts as a signal of its physiological state, reflecting the
interplay of environmental stimuli and intra-and extra-cellular processes. However, there is …

Cell-Based Simulations of Tissue Patterning During Morphogenesis

M Meer - 2022 - research-collection.ethz.ch
Spatial tissue patterning during early morphogenesis depends on the coordinated
movement and shape change of tissue cells. Therefore, the identification of the driving …

First person–Jean Castillo

J Castillo - Journal of Cell Science, 2021 - journals.biologists.com
First Person is a series of interviews with the first authors of a selection of papers published
in Journal of Cell Science, helping early-career researchers promote themselves alongside …