Various subgroups of CD8+ T lymphocytes do not only demonstrate cytotoxic effects, but
also serve important regulatory roles in the body's immune response. In particular, CD8+ …

Lung transplantation has developed significantly in recent years, but post-transplant care
and patients' survival still need to be improved. Moreover, organ shortage urges novel …

Since the rebirth of regulatory (formerly known as suppressor) T cells in the early 1990s,
research in the field of immune-regulation by various T cell populations has quickly gained …

Recently, it has been suggested that molecular hydrogen (H 2) can selectively reduce the
levels of hydroxyl radicals (. OH), and ameliorate oxidative and inflammatory injuries to …

Introduction Neuromyelitis optica spectrum disorder (NMOSD) is a group of antibody-
mediated inflammatory demyelinating central nervous system diseases. T lymphocytes …

Introduction Gaps still exist regarding knowledge on regulatory cells in transplant recipients.
We studied the phenotypic patterns of CD4+, CD8+ CD28-Tregs, and CD19+ IL-10+ Bregs …

The liver is considered a tolerogenic organ that can induce peripheral tolerance. The exact
mechanisms of tolerance in the liver remain undefined. Regulatory T cells (Tregs) have …

Background Immune monitoring of transplanted patients may provide a reliable basis for the
individualization of immunosuppressive therapy. In addition, it might be applied for realizing …

Aim Pirfenidone (PFD) has been used as medication for idiopathic pulmonary fibrosis due to
its ability in reducing lung fibrosis. However, the underlying mode of action in renal fibrosis …

Purpose:: Stem and progenitor cell transplantation provides a promising clinical application
for treating degenerative retinal diseases, including age-related macular degeneration …