Recent advances of chitosan formulations in biomedical applications

MAS Abourehab, S Pramanik, MA Abdelgawad… - International journal of …, 2022 - mdpi.com
Chitosan, a naturally abundant cationic polymer, is chemically composed of cellulose-based
biopolymers derived by deacetylating chitin. It offers several attractive characteristics such …

Recent progressions in biomedical and pharmaceutical applications of chitosan nanoparticles: A comprehensive review

EM Khalaf, NA Abood, RZ Atta… - International Journal of …, 2023 - Elsevier
Nowadays, the most common approaches in the prognosis, diagnosis, and treatment of
diseases are along with undeniable limitations. Thus, the ever-increasing need for using …

5-fluorouracil-loaded folic-acid-fabricated chitosan nanoparticles for site-targeted drug delivery cargo

S Ullah, AK Azad, A Nawaz, KU Shah, M Iqbal… - Polymers, 2022 - mdpi.com
Nanoparticles play a vital role in cancer treatment to deliver or direct the drug to the
malignant cell, avoiding the attacking of normal cells. The aim of the study is to formulate …

Formulation and evaluation of chitosan-gelatin thermosensitive hydrogels containing 5fu-alginate nanoparticles for skin delivery

A Nawaz, S Ullah, MA Alnuwaiser, FU Rehman… - Gels, 2022 - mdpi.com
(1) Background: Chitosan-gelatin-based thermosensitive hydrogel containing 5FU-alginate
nanoparticles was formulated for the effective and sustained delivery of 5FU to the skin.(2) …

Nanoparticles for antimicrobial agents delivery—An up-to-date review

DA Mercan, AG Niculescu, AM Grumezescu - International Journal of …, 2022 - mdpi.com
Infectious diseases constitute an increasing threat to public health and medical systems
worldwide. Particularly, the emergence of multidrug-resistant pathogens has left the …

Synthesis and Characterization of Acrylamide/Acrylic Acid Co-Polymers and Glutaraldehyde Crosslinked pH-Sensitive Hydrogels

MA Khan, AK Azad, M Safdar, A Nawaz, M Akhlaq… - Gels, 2022 - mdpi.com
This project aims to synthesize and characterize the pH-sensitive controlled release of 5-
fluorouracil (5-FU) loaded hydrogels (5-FULH) by polymerization of acrylamide (AM) and …

Formulation and optimization of alogliptin-loaded polymeric nanoparticles: In vitro to in vivo assessment

D Mohanty, SJ Gilani, A Zafar, SS Imam, LA Kumar… - Molecules, 2022 - mdpi.com
The nano-drug delivery system has gained greater acceptability for poorly soluble drugs.
Alogliptin (ALG) is a FDA-approved oral anti-hyperglycemic drug that inhibits dipeptidyl …

Novasomes as nano-vesicular carriers to enhance topical delivery of fluconazole: A new approach to treat fungal infections

I Fatima, A Rasul, S Shah, M Saadullah, N Islam… - Molecules, 2022 - mdpi.com
The occurrence of fungal infections has increased over the past two decades. It is observed
that superficial fungal infections are treated by conventional dosage forms, which are …

[HTML][HTML] Thiolated chitosan microneedle patch of levosulpiride from fabrication, characterization to bioavailability enhancement approach

R Habib, AK Azad, M Akhlaq, FA Al-Joufi, G Shahnaz… - Polymers, 2022 - mdpi.com
In this study, a first attempt has been made to deliver levosulpiride transdermally through a
thiolated chitosan microneedle patch (TC-MNP). Levosulpiride is slowly and weakly …

Full factorial design, physicochemical characterization, ex vivo investigation, and biological assessment of glutathione-loaded solid lipid nanoparticles for topical …

M Liu, M Sharma, GL Lu, Z Zhang, N Yin… - International journal of …, 2023 - Elsevier
Abstract l-Glutathione (GSH) has exceptional antioxidant activities against UVA irradiation-
induced oxidative stress and is used widely for combatting skin ageing. However, topical …