MFSD7c functions as a transporter of choline at the blood–brain barrier

XTA Nguyen, TNU Le, TQ Nguyen, H Thi Thuy Ha… - Cell Research, 2024 - nature.com
Mutations in the orphan transporter MFSD7c (also known as Flvcr2), are linked to Fowler
syndrome. Here, we used Mfsd7c knockout (Mfsd7c–/–) mice and cell-based assays to …

Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals

TC Kenny, A Khan, Y Son, L Yue, S Heissel, A Sharma… - Cell metabolism, 2023 - cell.com
Genome-wide association studies (GWASs) of serum metabolites have the potential to
uncover genes that influence human metabolism. Here, we combined an integrative genetic …