Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …

Background: Cannabidiol is being pursued as a therapeutic treatment for multiple
conditions, usually by oral delivery. Animal studies suggest oral bioavailability is low, but …

Background Public and medical interest in cannabidiol (CBD) has been rising, and CBD is
now available from various sources. Research into the effects of low-dose CBD on outcomes …

Clinical studies indicate that cannabidiol (CBD), the primary nonaddictive component of
cannabis that interacts with the serotonin (5-HT) 1A receptor, may possess analgesic and …

Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa
plants was studied. In this work, seven different plants were selected: three each from …

The golden age of cannabis pharmacology began in the 1960s as Raphael Mechoulam and
his colleagues in Israel isolated and synthesized cannabidiol, tetrahydrocannabinol, and …

1. Background Arthritis is a leading cause of pain, disfigurement, and disability in the United
States where nearly one-quarter of all adults have received an affirmative diagnosis. 2 …

Plants have had an essential role in the folklore of ancient cultures. In addition to the use as
food and spices, plants have also been utilized as medicines for over 5000 years. It is …

Background Current arthritis treatments often have side‐effects attributable to active
compounds as well as route of administration. Cannabidiol (CBD) attenuates inflammation …