Ancient pathogen genomics as an emerging tool for infectious disease research
Over the past decade, a genomics revolution, made possible through the development of
high-throughput sequencing, has triggered considerable progress in the study of ancient …
high-throughput sequencing, has triggered considerable progress in the study of ancient …
[图书][B] The archaeology of human bones
S Mays - 2021 - taylorfrancis.com
The Archaeology of Human Bones provides an up to date account of the analysis of human
skeletal remains from archaeological sites, introducing students to the anatomy of bones …
skeletal remains from archaeological sites, introducing students to the anatomy of bones …
[HTML][HTML] Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens,
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …
such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the …
[HTML][HTML] Ancient genomes reveal structural shifts after the arrival of Steppe-related ancestry in the Italian Peninsula
T Saupe, F Montinaro, C Scaggion, N Carrara… - Current Biology, 2021 - cell.com
Across Europe, the genetics of the Chalcolithic/Bronze Age transition is increasingly
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …
characterized in terms of an influx of Steppe-related ancestry. The effect of this major shift on …
One Health Approaches to Trace Mycobacterium leprae's Zoonotic Potential Through Time
Hansen's disease (leprosy), mainly caused by infection with Mycobacterium leprae, has
accompanied humanity for thousands of years. Although currently rare in Europe, there are …
accompanied humanity for thousands of years. Although currently rare in Europe, there are …
2000-year-old pathogen genomes reconstructed from metagenomic analysis of Egyptian mummified individuals
Background Recent advances in sequencing have facilitated large-scale analyses of the
metagenomic composition of different samples, including the environmental microbiome of …
metagenomic composition of different samples, including the environmental microbiome of …
Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus
AK Fotakis, SD Denham, M Mackie… - … of the Royal …, 2020 - royalsocietypublishing.org
Mineralized dental plaque (calculus) has proven to be an excellent source of ancient
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …
biomolecules. Here we present a Mycobacterium leprae genome (6.6-fold), the causative …
Infectious diseases and Neolithic transformations: Evaluating biological and archaeological proxies in the German loess zone between 5500 and 2500 BCE
K Fuchs, C Rinne, C Drummer, A Immel… - The …, 2019 - journals.sagepub.com
It is a common assumption that–compared with the Mesolithic–the adoption of Neolithic
lifeways was accompanied by a higher risk of infection and the development of epidemic …
lifeways was accompanied by a higher risk of infection and the development of epidemic …
Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes
Background Hansen's disease (leprosy), widespread in medieval Europe, is today mainly
prevalent in tropical and subtropical regions with around 200,000 new cases reported …
prevalent in tropical and subtropical regions with around 200,000 new cases reported …
Evolutionary history of Mycobacterium leprae in the Pacific Islands
KE Blevins, AE Crane, C Lum… - … of the Royal …, 2020 - royalsocietypublishing.org
As one of the oldest known human diseases, leprosy or Hansen's disease remains a public
health concern around the world with over 200 000 new cases in 2018. Most human leprosy …
health concern around the world with over 200 000 new cases in 2018. Most human leprosy …