Stress and strain within the lung
L Gattinoni, E Carlesso, P Caironi - Current opinion in critical care, 2012 - journals.lww.com
Stress and strain within the lung : Current Opinion in Critical Care Stress and strain within the
lung : Current Opinion in Critical Care Log in or Register Subscribe to journalSubscribe Get …
lung : Current Opinion in Critical Care Log in or Register Subscribe to journalSubscribe Get …
Bioactive extracellular matrix fragments in lung health and disease
A Gaggar, N Weathington - The Journal of clinical …, 2016 - Am Soc Clin Investig
The extracellular matrix (ECM) is the noncellular component critical in the maintenance of
organ structure and the regulation of tissue development, organ structure, and cellular …
organ structure and the regulation of tissue development, organ structure, and cellular …
The mechanical memory of lung myofibroblasts
JL Balestrini, S Chaudhry, V Sarrazy… - Integrative …, 2012 - academic.oup.com
Fibroblasts differentiate into the highly synthetic and contractile myofibroblast phenotype
when exposed to substrates with an elastic modulus corresponding to pathologically stiff …
when exposed to substrates with an elastic modulus corresponding to pathologically stiff …
Algal carbohydrate polymers: Catalytic innovations for sustainable development
Algal polysaccharides, harnessed for their catalytic potential, embody a compelling narrative
in sustainable chemistry. This review explores the complex domains of algal carbohydrate …
in sustainable chemistry. This review explores the complex domains of algal carbohydrate …
[HTML][HTML] Mechanics of pulmonary airways: linking structure to function through constitutive modeling, biochemistry, and histology
Breathing involves fluid-solid interactions in the lung; however, the lack of experimental data
inhibits combining the mechanics of air flow to airway deformation, challenging the …
inhibits combining the mechanics of air flow to airway deformation, challenging the …
Mechanical load induces a 100-fold increase in the rate of collagen proteolysis by MMP-1
AS Adhikari, J Chai, AR Dunn - Biophysical Journal, 2011 - cell.com
Both mechanotransduction and extracellular matrix (ECM) proteolytic remodeling are critical
during embryonic development and in disease progression. Although mechanical stress is …
during embryonic development and in disease progression. Although mechanical stress is …
Nonlinear elasticity of the lung extracellular microenvironment is regulated by macroscale tissue strain
The extracellular matrix (ECM) of the lung provides physical support and key mechanical
signals to pulmonary cells. Although lung ECM is continuously subjected to different stretch …
signals to pulmonary cells. Although lung ECM is continuously subjected to different stretch …
Emphysema and mechanical stress-induced lung remodeling
Transpulmonary pressure and the mechanical stresses of breathing modulate many
essential cell functions in the lung via mechanotransduction. We review how mechanical …
essential cell functions in the lung via mechanotransduction. We review how mechanical …
[HTML][HTML] Anti-CELA1 antibody KF4 prevents emphysema by inhibiting stretch-mediated remodeling
There are no therapies to prevent emphysema progression. Chymotrypsin-like elastase 1
(CELA1) is a serine protease that binds and cleaves lung elastin in a stretch-dependent …
(CELA1) is a serine protease that binds and cleaves lung elastin in a stretch-dependent …
Computed tomography measure of lung at risk and lung function decline in chronic obstructive pulmonary disease
Rationale: The rate of decline of lung function is greater than age-related change in a
substantial proportion of patients with chronic obstructive pulmonary disease, even after …
substantial proportion of patients with chronic obstructive pulmonary disease, even after …