Photodynamic therapy—current limitations and novel approaches
Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …
Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics
S Singh, A Aggarwal, NVSDK Bhupathiraju… - Chemical …, 2015 - ACS Publications
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …
Synthetic pathways to water-soluble phthalocyanines and close analogs
Synthetic pathways to water-soluble phthalocyanines and close analogs - ScienceDirect Skip
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Comparative studies of photophysical and photochemical properties of solketal substituted platinum (II) and zinc (II) phthalocyanine sets
A complete set of platinum (II) solketal substituted phthalocyanines has been synthesized
and characterized. To evaluate their potential as Type II photosensitizers for photodynamic …
and characterized. To evaluate their potential as Type II photosensitizers for photodynamic …
A set of highly water-soluble tetraethyleneglycol-substituted Zn (II) phthalocyanines: synthesis, photochemical and photophysical properties, interaction with plasma …
S Tuncel, F Dumoulin, J Gailer… - Dalton …, 2011 - pubs.rsc.org
Three Zn (II) phthalocyanines substituted by hydroxyl-terminated tetraethylene glycol chains
have been synthesized. In order to evaluate the potential of these highly water-soluble …
have been synthesized. In order to evaluate the potential of these highly water-soluble …
Fluorescent glycoconjugates and their applications
B Thomas, KC Yan, XL Hu… - Chemical Society …, 2020 - pubs.rsc.org
Glycoconjugates and their applications as lectin ligands in biology have been thoroughly
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …
Light-triggered liposomal release: membrane permeabilization by photodynamic action
A Pashkovskaya, E Kotova, Y Zorlu, F Dumoulin… - Langmuir, 2010 - ACS Publications
Photosensitized damage to liposome membranes was studied by using different dye-
leakage assays based on fluorescence dequenching of a series of dyes upon their release …
leakage assays based on fluorescence dequenching of a series of dyes upon their release …
Synthesis and photophysical properties of thioglycosylated chlorins, isobacteriochlorins, and bacteriochlorins for bioimaging and diagnostics
S Singh, A Aggarwal, S Thompson… - Bioconjugate …, 2010 - ACS Publications
The facile synthesis and photophysical properties of three nonhydrolyzable thioglycosylated
porphyrinoids are reported. Starting from meso-perfluorophenylporphyrin, the …
porphyrinoids are reported. Starting from meso-perfluorophenylporphyrin, the …
An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex
K Kawauchi, W Sugimoto, T Yasui, K Murata… - Nature …, 2018 - nature.com
Aberrant activation of RAS signalling pathways contributes to aggressive phenotypes of
cancer cells. The RAS-targeted therapies for cancer, therefore, have been recognised to be …
cancer cells. The RAS-targeted therapies for cancer, therefore, have been recognised to be …
Monoglycoconjugated water-soluble phthalocyanines. Design and synthesis of potential selectively targeting PDT photosensitisers
Monoglycoconjugated water-soluble phthalocyanines. Design and synthesis of potential
selectively targeting PDT photosensitisers - ScienceDirect Skip to main contentSkip to article …
selectively targeting PDT photosensitisers - ScienceDirect Skip to main contentSkip to article …