Photodynamic therapy—current limitations and novel approaches

G Gunaydin, ME Gedik, S Ayan - Frontiers in Chemistry, 2021 - frontiersin.org
Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the
excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be …

Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics

S Singh, A Aggarwal, NVSDK Bhupathiraju… - Chemical …, 2015 - ACS Publications
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …

Synthetic pathways to water-soluble phthalocyanines and close analogs

F Dumoulin, M Durmuş, V Ahsen, T Nyokong - Coordination Chemistry …, 2010 - Elsevier
Synthetic pathways to water-soluble phthalocyanines and close analogs - ScienceDirect Skip
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Comparative studies of photophysical and photochemical properties of solketal substituted platinum (II) and zinc (II) phthalocyanine sets

Y Zorlu, F Dumoulin, M Durmuş, V Ahsen - Tetrahedron, 2010 - Elsevier
A complete set of platinum (II) solketal substituted phthalocyanines has been synthesized
and characterized. To evaluate their potential as Type II photosensitizers for photodynamic …

A set of highly water-soluble tetraethyleneglycol-substituted Zn (II) phthalocyanines: synthesis, photochemical and photophysical properties, interaction with plasma …

S Tuncel, F Dumoulin, J Gailer… - Dalton …, 2011 - pubs.rsc.org
Three Zn (II) phthalocyanines substituted by hydroxyl-terminated tetraethylene glycol chains
have been synthesized. In order to evaluate the potential of these highly water-soluble …

Fluorescent glycoconjugates and their applications

B Thomas, KC Yan, XL Hu… - Chemical Society …, 2020 - pubs.rsc.org
Glycoconjugates and their applications as lectin ligands in biology have been thoroughly
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …

Light-triggered liposomal release: membrane permeabilization by photodynamic action

A Pashkovskaya, E Kotova, Y Zorlu, F Dumoulin… - Langmuir, 2010 - ACS Publications
Photosensitized damage to liposome membranes was studied by using different dye-
leakage assays based on fluorescence dequenching of a series of dyes upon their release …

Synthesis and photophysical properties of thioglycosylated chlorins, isobacteriochlorins, and bacteriochlorins for bioimaging and diagnostics

S Singh, A Aggarwal, S Thompson… - Bioconjugate …, 2010 - ACS Publications
The facile synthesis and photophysical properties of three nonhydrolyzable thioglycosylated
porphyrinoids are reported. Starting from meso-perfluorophenylporphyrin, the …

An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex

K Kawauchi, W Sugimoto, T Yasui, K Murata… - Nature …, 2018 - nature.com
Aberrant activation of RAS signalling pathways contributes to aggressive phenotypes of
cancer cells. The RAS-targeted therapies for cancer, therefore, have been recognised to be …

Monoglycoconjugated water-soluble phthalocyanines. Design and synthesis of potential selectively targeting PDT photosensitisers

Y Zorlu, F Dumoulin, D Bouchu, V Ahsen, D Lafont - Tetrahedron Letters, 2010 - Elsevier
Monoglycoconjugated water-soluble phthalocyanines. Design and synthesis of potential
selectively targeting PDT photosensitisers - ScienceDirect Skip to main contentSkip to article …