[HTML][HTML] The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

HM Habib, S Ibrahim, A Zaim, WH Ibrahim - Biomedicine & …, 2021 - Elsevier
Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19.
Indeed, several of the manifestations of COVID-19, such as inflammation, hypercoagulation …

Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

[HTML][HTML] The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria

DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

Lactoferrin: major physiological functions and applications

L Hao, Q Shan, J Wei, F Ma… - Current Protein and …, 2019 - ingentaconnect.com
Lactoferrin (lactotransferrin; Lf) is an iron-binding glycoprotein and one of the most important
bioactivators in milk and other external secretions. It has numerous biological roles …

Lactoferrin: A glycoprotein involved in immunomodulation, anticancer, and antimicrobial processes

Q Rascón-Cruz, EA Espinoza-Sánchez… - Molecules, 2021 - mdpi.com
Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in
apoptotic processes in cancer cells, its ability to modulate various reactions of the immune …

Lung microbiota in the acute respiratory disease: from coronavirus to metabolomics

V Fanos, MC Pintus, R Pintus… - Journal of Pediatric and …, 2020 - jpnim.com
Healthy lungs are not sterile. In the last decade, it was demonstrated that the healthy lung
has its specific microbiota. It is much smaller in numerical terms, compared to the gut …

Nutraceutical and health-promoting potential of lactoferrin, an iron-binding protein in human and animal: current knowledge

MF Ashraf, D Zubair, MN Bashir, M Alagawany… - … Trace Element Research, 2024 - Springer
Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in
bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile …

[HTML][HTML] Evaluating the in vitro efficacy of bovine lactoferrin products against SARS-CoV-2 variants of concern

JW Wotring, R Fursmidt, L Ward, JZ Sexton - Journal of Dairy Science, 2022 - Elsevier
Bovine lactoferrin (bLF), a naturally occurring glycoprotein found in milk, has bioactive
characteristics against many microbes, viruses, and other pathogens. Bovine lactoferrin …

Lactoferrin and its derived peptides: An alternative for combating virulence mechanisms developed by pathogens

D Zarzosa-Moreno, C Avalos-Gómez… - Molecules, 2020 - mdpi.com
Due to the emergence of multidrug-resistant pathogens, it is necessary to develop options to
fight infections caused by these agents. Lactoferrin (Lf) is a cationic nonheme multifunctional …

Lactoferrin for the treatment of COVID‑19

Y Wang, P Wang, H Wang, Y Luo… - Experimental and …, 2020 - spandidos-publications.com
Abstract The coronavirus disease 2019 (COVID‑19) outbreak was caused by infection with
the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). The clinical outcomes …