Clinical and experimental insight into pathophysiology, comorbidity and therapy of absence seizures
Absence seizures in children and teenagers are generally considered relatively benign
because of their non-convulsive nature and the large incidence of remittance in early …
because of their non-convulsive nature and the large incidence of remittance in early …
Cognitive and neurodevelopmental comorbidities in paediatric epilepsy
KC Nickels, MJ Zaccariello, LD Hamiwka… - Nature Reviews …, 2016 - nature.com
Cognitive and behavioural comorbidities are often seen in children with epilepsy, and are
more common and severe in refractory epilepsy. These comorbidities are associated with …
more common and severe in refractory epilepsy. These comorbidities are associated with …
Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence
AM Kanner, SC Schachter, JJ Barry, DC Hersdorffer… - Epilepsy & Behavior, 2012 - Elsevier
Depression is the most frequent psychiatric comorbidity in people with epilepsy (PWE) with
lifetime prevalence rates ranging between 30 and 35%. Multifactorial variables play a …
lifetime prevalence rates ranging between 30 and 35%. Multifactorial variables play a …
Depression and epilepsy: a bidirectional relation?
AM Kanner - Epilepsia, 2011 - Wiley Online Library
A bidirectional relation between depressive disorders and epilepsy has been suggested by
several population‐based studies and is supported by experimental studies. This article …
several population‐based studies and is supported by experimental studies. This article …
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures
E Tringham, KL Powell, SM Cain, K Kuplast… - Science translational …, 2012 - science.org
Absence seizures are a common seizure type in children with genetic generalized epilepsy
and are characterized by a temporary loss of awareness, arrest of physical activity, and …
and are characterized by a temporary loss of awareness, arrest of physical activity, and …
The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depressiony
K Sarkisova, G van Luijtelaar - Progress in Neuro-Psychopharmacology …, 2011 - Elsevier
A great number of clinical observations show a relationship between epilepsy and
depression. Idiopathic generalized epilepsy, including absence epilepsy, has a genetic …
depression. Idiopathic generalized epilepsy, including absence epilepsy, has a genetic …
Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy
Survivors of traumatic brain injury (TBI) often develop chronic neurological, neurocognitive,
psychological, and psychosocial deficits that can have a profound impact on an individual's …
psychological, and psychosocial deficits that can have a profound impact on an individual's …
Issues related to symptomatic and disease‐modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy
Many symptoms of neurologic or psychiatric illness—such as cognitive impairment,
depression, anxiety, attention deficits, and migraine—occur more frequently in people with …
depression, anxiety, attention deficits, and migraine—occur more frequently in people with …
Neuropsychiatric symptomatology predicts seizure recurrence in newly treated patients
Objectives: To test the hypothesis that neuropsychiatric symptomatology is predictive of the
success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that …
success of seizure control in patients newly treated with antiepileptic drugs (AEDs), and that …
The anticonvulsant effects of cannabidiol in experimental models of epileptic seizures: From behavior and mechanisms to clinical insights
W Lazarini-Lopes, RA Do Val-da Silva… - Neuroscience & …, 2020 - Elsevier
Epilepsy is a neurological disorder characterized by the presence of seizures and
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …