Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

The development of targeted medicine has greatly expanded treatment options and spurred
new research avenues in cancer therapeutics, with monoclonal antibodies (mAbs) emerging …

Nanobodies (Nbs), the variable domains of camelid heavy chain-only antibodies, are a
promising class of therapeutics or in vivo imaging reagents entering the clinic. They possess …

A compound's intratumoural distribution is an important determinant for the effectiveness of
molecular therapy or imaging. Antibodies (Abs), though often used in the design of targeted …

In spite of the successful use of monoclonal antibodies (mAbs) in clinic for tumor treatment,
their applications are still hampered in therapeutic development due to limitations, such as …

For treatment and diagnosis of cancer, antibodies have proven their value and now serve as
a first line of therapy for certain cancers. A unique class of antibody fragments called …

Targeted therapy and immunotherapy have become mainstream in cancer treatment.
However, only patient subsets benefit from these expensive therapies, and often responses …

Macrophages play an important role throughout the body. Antiinflammatory macrophages
expressing the macrophage mannose receptor (MMR, CD206) are involved in disease …

Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …

Molecular imaging is paving the way towards noninvasive detection, staging, and treatment
follow-up of diseases such as cancer and inflammation-related conditions. Monoclonal …