Preterm birth which occurs before 37 weeks gestation is one of the most common obstetrical
complication in humans. After many studies, it appears that “not one answer fits all” …

Human parturition at term and preterm is an inflammatory process synchronously executed
by both fetomaternal tissues to transition them from a quiescent state t an active state of …

Preterm birth (PTB;< 37 weeks of gestation) impacts∼ 11% of all pregnancies and
contributes to 1 million neonatal deaths worldwide annually. An understanding of the feto …

Background Fetal endocrine signals are generally considered to contribute to the timing of
birth and the initiation of labor. Fetal tissues under oxidative stress release inflammatory …

At term, the signals of fetal maturity and feto-placental tissue aging prompt uterine readiness
for delivery by transitioning quiescent myometrium to an active stage. It is still unclear how …

Maternal infection (ie, ascending infection) and the resulting host inflammatory response are
risk factors associated with spontaneous preterm birth (PTB), a major pregnancy …

Simple Summary Labour is considered a painful episode where complex physiological,
hormonal, morphological, and behavioural changes are present. During animal parturition …

Oxidative stress (OS) and inflammation arising from cellular derangements at the fetal
membrane-decidual interface (feto-maternal interface [FMi]) is a major antecedent to preterm …

Cellular senescence (CS) is defined as a state of terminal proliferation arrest accompanied
by morphological alterations, pro-inflammatory phenotype, and metabolic changes. In recent …

Amnion epithelial cell (AEC) shedding causes microfractures in human placental
membranes during gestation. However, microfractures are healed to maintain membrane …