Heterogeneous catalysis in continuous flow microreactors: A review of methods and applications

A Tanimu, S Jaenicke, K Alhooshani - Chemical Engineering Journal, 2017 - Elsevier
Over the past two decades, microreactor technology has evolved to become a crucial
component in the development of process intensification. Microreactors have helped to …

Recent advances in Sonogashira reactions

R Chinchilla, C Nájera - Chemical Society Reviews, 2011 - pubs.rsc.org
The coupling of aryl or vinyl halides with terminal acetylenes catalysed by palladium and
other transition metals, commonly termed as Sonogashira cross-coupling reaction, is one of …

Supported catalysis in continuous‐flow microreactors

R Munirathinam, J Huskens… - Advanced synthesis & …, 2015 - Wiley Online Library
This review surveys the recent developments to perform heterogeneous catalysis in
continuous‐flow microreactors. Three different types, namely,(i) packed‐bed,(ii) monolithic …

Immobilization of N-heterocyclic carbene compounds: a synthetic perspective

R Zhong, AC Lindhorst, FJ Groche… - Chemical Reviews, 2017 - ACS Publications
Over the course of the past 15 years the success story of N-heterocyclic carbene (NHC)
compounds in organic, inorganic, and organometallic chemistry has been extended to …

Cross-coupling in flow

T Noël, SL Buchwald - Chemical Society Reviews, 2011 - pubs.rsc.org
Until recently, cross-coupling reactions have been exclusively performed in batch
processes. With the advent of microfluidics, significant effort has been devoted to develop a …

[图书][B] Palladium-catalyzed coupling reactions: practical aspects and future developments

Á Molnár - 2013 - books.google.com
This handbook and ready reference brings together all significant issues of practical
importance in selected topics discussing recent significant achievements for interested …

Heterogeneous catalytic synthesis using microreactor technology

CG Frost, L Mutton - Green Chemistry, 2010 - pubs.rsc.org
The application of heterogeneous catalysis in conjunction with microreactor technology can
facilitate a cleaner and scalable flow methodology for organic synthesis. In this tutorial …

Immobilized transition metals as catalysts for cross‐couplings in continuous flow—a critical assessment of the reaction mechanism and metal leaching

D Cantillo, CO Kappe - ChemCatChem, 2014 - Wiley Online Library
In the not too distant future many industrially important chemicals (including
pharmaceuticals) will probably be manufactured using continuous flow technology. For a …

Chemical reaction engineering, process design and scale-up issues at the frontier of synthesis: Flow chemistry

I Rossetti, M Compagnoni - Chemical Engineering Journal, 2016 - Elsevier
Flow chemistry has been proposed in modern organic chemistry as a mean for process
intensification, to improve the control over reaction performance and to achieve higher yield …

[图书][B] Micro reaction technology in organic synthesis

C Wiles, P Watts - 2016 - books.google.com
A valuable resource for the modern synthetic chemist, this broadly applicable book
addresses the multidisciplinary field of micro reaction technology-from novel research …