The Complete Assessment of Small Molecule and Peptidomimetic Inhibitors of Sortase A Towards Antivirulence Treatment

JCJ Hintzen, H Abujubara, D Tietze… - … –A European Journal, 2024 - Wiley Online Library
This review covers the most recent advances in the development of inhibitors for the
bacterial enzyme sortase A (SrtA). Sortase A (SrtA) is a critical virulence factor, present …

Current View on Major Natural Compounds Endowed with Antibacterial and Antiviral Effects

R Arrigoni, A Ballini, E Jirillo, L Santacroce - Antibiotics, 2024 - mdpi.com
Nowadays, infectious diseases of bacterial and viral origins represent a serious medical
problem worldwide. In fact, the development of antibiotic resistance is responsible for the …

Harnessing the combined effect of antivirulence agent trans-chalcone with bactericidal curcumin against sortase A enzyme to tackle Gram-positive bacterial infections

P Kumari, SK Banerjee, US Murty, V Ravichandiran… - Folia Microbiologica, 2024 - Springer
Gram-positive bacteria are responsible for a wide range of infections in humans. In most
Gram-positive bacteria, sortase A plays a significant role in attaching virulence factors to the …