Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review
D Singh, A Agusti, FJ Martinez, A Papi… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …
Dupilumab for COPD with blood eosinophil evidence of type 2 inflammation
Background Dupilumab, a fully human monoclonal antibody that blocks the shared receptor
component for interleukin-4 and interleukin-13, key and central drivers of type 2 …
component for interleukin-4 and interleukin-13, key and central drivers of type 2 …
Inflammatory endotypes in COPD
PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …
poorly treated by current therapies as it has proved difficult to treat the underlying …
Benralizumab for the prevention of COPD exacerbations
GJ Criner, BR Celli, CE Brightling… - … England Journal of …, 2019 - Mass Medical Soc
Background The efficacy and safety of benralizumab, an interleukin-5 receptor alpha–
directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with …
directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with …
Prognostic risk factors for moderate-to-severe exacerbations in patients with chronic obstructive pulmonary disease: a systematic literature review
Background Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality worldwide. COPD exacerbations are associated with a worsening of lung …
and mortality worldwide. COPD exacerbations are associated with a worsening of lung …
Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits
AG Mathioudakis, W Janssens, P Sivapalan… - Thorax, 2020 - thorax.bmj.com
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with a
significant mortality, health and economic burden. Their diagnosis, assessment and …
significant mortality, health and economic burden. Their diagnosis, assessment and …
Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics
K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2022 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …
diseases, that share a number of common causative factors including cigarette smoking …
Chronic obstructive pulmonary disease biomarkers and their interpretation
RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …
abnormal inflammatory process resulting in tissue damage with ineffective repair in …
Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label …
P Sivapalan, TS Lapperre, J Janner… - The Lancet …, 2019 - thelancet.com
Background Treatment with systemic corticosteroids in patients with acute exacerbations of
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse …
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse …