Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review

D Singh, A Agusti, FJ Martinez, A Papi… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Dupilumab for COPD with blood eosinophil evidence of type 2 inflammation

SP Bhatt, KF Rabe, NA Hanania… - … England Journal of …, 2024 - Mass Medical Soc
Background Dupilumab, a fully human monoclonal antibody that blocks the shared receptor
component for interleukin-4 and interleukin-13, key and central drivers of type 2 …

Inflammatory endotypes in COPD

PJ Barnes - Allergy, 2019 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a major global health problem that is
poorly treated by current therapies as it has proved difficult to treat the underlying …

Benralizumab for the prevention of COPD exacerbations

GJ Criner, BR Celli, CE Brightling… - … England Journal of …, 2019 - Mass Medical Soc
Background The efficacy and safety of benralizumab, an interleukin-5 receptor alpha–
directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with …

Prognostic risk factors for moderate-to-severe exacerbations in patients with chronic obstructive pulmonary disease: a systematic literature review

JR Hurst, MLK Han, B Singh, S Sharma, G Kaur… - Respiratory …, 2022 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality worldwide. COPD exacerbations are associated with a worsening of lung …

Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits

AG Mathioudakis, W Janssens, P Sivapalan… - Thorax, 2020 - thorax.bmj.com
Acute exacerbations of chronic obstructive pulmonary disease (COPD) are associated with a
significant mortality, health and economic burden. Their diagnosis, assessment and …

Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics

K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2022 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …

Chronic obstructive pulmonary disease biomarkers and their interpretation

RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label …

P Sivapalan, TS Lapperre, J Janner… - The Lancet …, 2019 - thelancet.com
Background Treatment with systemic corticosteroids in patients with acute exacerbations of
chronic obstructive pulmonary disease (COPD) is associated with debilitating adverse …

[引用][C] Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019

D Singh, A Agusti, A Anzueto, PJ Barnes… - European …, 2019 - Eur Respiratory Soc