[HTML][HTML] The HSP90 family: structure, regulation, function, and implications in health and disease

A Hoter, ME El-Sabban, HY Naim - International journal of molecular …, 2018 - mdpi.com
The mammalian HSP90 family of proteins is a cluster of highly conserved molecules that are
involved in myriad cellular processes. Their distribution in various cellular compartments …

[HTML][HTML] Polyphenism–a window into gene-environment interactions and phenotypic plasticity

CH Yang, J Andrew Pospisilik - Frontiers in genetics, 2019 - frontiersin.org
Phenotypic plasticity describes the capacity of a single genotype to exhibit a variety of
phenotypes as well as the mechanisms that translate environmental variation into …

[HTML][HTML] A histone demethylase links the loss of plasticity to nongenetic inheritance and morphological change

NA Levis, EJ Ragsdale - Nature Communications, 2023 - nature.com
Plasticity is a widespread feature of development, enabling phenotypic change based on the
environment. Although the evolutionary loss of plasticity has been linked both theoretically …

A Mediator subunit imparts robustness to a polyphenism decision

S Casasa, E Katsougia… - Proceedings of the …, 2023 - National Acad Sciences
Polyphenism is a type of developmental plasticity that translates continuous environmental
variability into discontinuous phenotypes. Such discontinuity likely requires a switch …

[HTML][HTML] Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell

B Sieriebriennikov, S Sun, JW Lightfoot, H Witte… - PLoS …, 2020 - journals.plos.org
Environment shapes development through a phenomenon called developmental plasticity.
Deciphering its genetic basis has potential to shed light on the origin of novel traits and …

Geometric morphometrics of microscopic animals as exemplified by model nematodes

T Theska, B Sieriebriennikov, SS Wighard… - Nature …, 2020 - nature.com
While a host of molecular techniques are utilized by evolutionary developmental (evo-devo)
biologists, tools for quantitative evaluation of morphology are still largely underappreciated …

[PDF][PDF] Physiological mechanisms and the evolution of plasticity

CC Ledón-Rettig, EJ Ragsdale - Phenotypic plasticity & evolution, 2021 - library.oapen.org
Phenotypic plasticity is fundamentally a physiological phenomenon. Whether the phenotypic
outcome of plasticity is the preservation of form ('homeostasis'), fleeting change, more …

[HTML][HTML] Co-option of an astacin metalloprotease is associated with an evolutionarily novel feeding morphology in a predatory nematode

Y Ishita, A Onodera, T Ekino, T Chihara… - Molecular Biology and …, 2023 - ncbi.nlm.nih.gov
Animals consume a wide variety of food sources to adapt to different environments.
However, the genetic mechanisms underlying the acquisition of evolutionarily novel feeding …

[HTML][HTML] Chitin contributes to the formation of a feeding structure in a predatory nematode

S Sun, H Witte, RJ Sommer - Current Biology, 2023 - cell.com
Some nematode predators and parasites form teeth-like denticles that are histologically
different from vertebrate teeth, but their biochemical composition remains elusive. Here, we …

Multiple plasticity regulators reveal targets specifying an induced predatory form in nematodes

LT Bui, EJ Ragsdale - Molecular Biology and Evolution, 2019 - academic.oup.com
The ability to translate a single genome into multiple phenotypes, or developmental
plasticity, defines how phenotype derives from more than just genes. However, to study the …