Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities

Z Cheng, A Al Zaki, JZ Hui, VR Muzykantov, A Tsourkas - Science, 2012 - science.org
Nanoparticle-based drug delivery systems have been developed to improve the efficacy and
reduce the systemic toxicity of a wide range of drugs. Although clinically approved …

Theranostics: combining imaging and therapy

SS Kelkar, TM Reineke - Bioconjugate chemistry, 2011 - ACS Publications
Employing theranostic nanoparticles, which combine both therapeutic and diagnostic
capabilities in one dose, has promise to propel the biomedical field toward personalized …

Surface modification using phosphonic acids and esters

C Queffélec, M Petit, P Janvier, DA Knight… - Chemical …, 2012 - ACS Publications
1. INTRODUCTION The design of organically modified surfaces is a rapidly expanding field
of research in materials science in which the central purpose is access to materials …

[HTML][HTML] Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy

MK Yu, J Park, S Jon - Theranostics, 2012 - ncbi.nlm.nih.gov
Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional
nanoparticles harboring various functions including targeting, imaging, therapy, and etc …

Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

K Zarschler, L Rocks, N Licciardello, L Boselli… - … , Biology and Medicine, 2016 - Elsevier
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

Nanotheranostics for personalized medicine

S Mura, P Couvreur - Advanced drug delivery reviews, 2012 - Elsevier
The application of nanotechnology in the biomedical field, known as nanomedicine, has
gained much interest in the recent past, as versatile strategy for selective drug delivery and …

Development of mesoporous silica-based nanoparticles with controlled release capability for cancer therapy

H Mekaru, J Lu, F Tamanoi - Advanced drug delivery reviews, 2015 - Elsevier
Nanoparticles that respond to internal and external stimuli to carry out controlled release of
anticancer drugs have been developed. In this review, we focus on the development of …

Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation

A Kunzmann, B Andersson, T Thurnherr, H Krug… - … et Biophysica Acta (BBA …, 2011 - Elsevier
BACKGROUND: It is widely believed that engineered nanomaterials will be increasingly
used in biomedical applications. However, before these novel materials can be safely …