Mitochondrial myopathy encephalopathy lactic acidosis and stroke-like episodes (MELAS) is
an important cause of stroke-mimicking diseases that predominantly affect patients before …

Mitochondrial diseases are one of the largest groups of neurological genetic disorders.
Despite continuous efforts of the scientific community, no cure has been developed, and …

Background and purpose Patients with neuromuscular conditions are at increased risk of
suffering perioperative complications related to anaesthesia. There is currently little specific …

Background and Objectives Primary mitochondrial myopathies (PMMs) encompass a group
of genetic disorders that impair mitochondrial oxidative phosphorylation, adversely affecting …

Mitochondrial diseases are a heterogeneous group of monogenic disorders that result from
impaired oxidative phosphorylation (OXPHOS). As neuromuscular tissues are highly energy …

Background Mitochondrial dysfunction caused by mitochondrial (mtDNA) deletions have
been associated with skeletal muscle atrophy and myofibre loss. However, whether such …

Abstract Background Mitochondrial DNA (mtDNA) deletion mutations lead to electron
transport chain-deficient cells and age-induced cell loss in multiple tissues and mammalian …

Background Oxidative stress (OS) and mitochondrial alterations have been implicated in the
pathogenesis of rheumatoid arthritis (RA). Various environmental triggers like air pollutants …

Disruption of mitochondrial function is a common feature of inherited mitochondrial diseases
(mitochondriopathies) and many other infectious and non-infectious diseases including viral …

Selenoprotein N (SEPN1) is a protein of the endoplasmic reticulum (ER) whose inherited
defects originate SEPN1-related myopathy (SEPN1-RM). Here, we identify an interaction …