The classification, molecular structure and biological biosynthesis of flavonoids, and their roles in biotic and abiotic stresses

WB Zhuang, YH Li, XC Shu, YT Pu, XJ Wang, T Wang… - Molecules, 2023 - mdpi.com
With the climate constantly changing, plants suffer more frequently from various abiotic and
biotic stresses. However, they have evolved biosynthetic machinery to survive in stressful …

Flavonoid production: current trends in plant metabolic engineering and de novo microbial production

H Tariq, S Asif, A Andleeb, C Hano, BH Abbasi - Metabolites, 2023 - mdpi.com
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …

Metabolic engineering of microorganisms for the production of flavonoids

H Sheng, X Sun, Y Yan, Q Yuan, J Wang… - … in bioengineering and …, 2020 - frontiersin.org
Flavonoids are a class of secondary metabolites found in plant and fungus. They have been
widely used in food, pharmaceutical, and nutraceutical industries owing to their significant …

Metabolic engineering of microbial cell factories for biosynthesis of flavonoids: A review

H Lou, L Hu, H Lu, T Wei, Q Chen - Molecules, 2021 - mdpi.com
Flavonoids belong to a class of plant secondary metabolites that have a polyphenol
structure. Flavonoids show extensive biological activity, such as antioxidative, anti …

De novo biosynthesis of complex natural product sakuranetin using modular co-culture engineering

X Wang, Z Li, L Policarpio, MAG Koffas… - Applied microbiology and …, 2020 - Springer
Flavonoids are a large family of plant and fungal natural products, among which many have
been found to possess outstanding biological activities. Utilization of engineered microbes …

De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae

X Liu, J Cheng, X Zhu, G Zhang, S Yang… - ACS synthetic …, 2020 - ACS Publications
Pinocembrin derived flavones are the major bioactive compounds presented in the
Lamiaceae plants that have long been of interest due to their great pharmaceutical and …

Enhancing Flavan-3-ol Biosynthesis in Saccharomyces cerevisiae

C Sun, G Li, H Li, Y Lyu, S Yu… - Journal of Agricultural and …, 2021 - ACS Publications
Flavan-3-ols are a group of flavonoids that exert beneficial effects. This study aimed to
enhance key metabolic processes related to flavan-3-ols biosynthesis. The engineered …

First Natural Yeast Strain Trichosporon asahii HZ10 with Robust Flavonoid Productivity and Its Potential Biosynthetic Pathway

SJ Xue, J Liu, XC Li, XT Zhang, ZZ Xin… - Journal of Agricultural …, 2023 - ACS Publications
Flavonoids are generally thought to be essential plant natural products with diverse
bioactivities and pharmacological effects. Conventional approaches for the industrial …

Optimization of Pinocembrin Biosynthesis in Saccharomyces cerevisiae

M Tous Mohedano, J Mao, Y Chen - ACS Synthetic Biology, 2022 - ACS Publications
The flavonoid pinocembrin and its derivatives have gained increasing interest for their
benefits on human health. While pinocembrin and its derivatives can be produced in …

Bioproduction process of natural products and biopharmaceuticals: Biotechnological aspects

I Süntar, S Çetinkaya, ÜS Haydaroğlu… - Biotechnology …, 2021 - Elsevier
Decades of research have been put in place for developing sustainable routes of
bioproduction of high commercial value natural products (NPs) on the global market. In the …