Neurological disorders affecting the central nervous system (CNS) are still incompletely
understood. Many of these disorders lack a cure and are seeking more specific and effective …

Abstract The first CD19 CAR T-cell products, Kymriah and Yescarta, are entering the US
market and also being evaluated for marketing authorization in the EU. This breakthrough …

Genome-editing technology has enabled scientists to make changes in model organisms'
DNA at the genomic level to get biotechnologically important products from them. Most …

Fruit crops, including apple, orange, grape, banana, strawberry, watermelon, kiwifruit and
tomato, not only provide essential nutrients for human life but also contribute to the major …

CRISPR/Cas technology of genome editing is a powerful tool for making targeted changes
in the DNA of various organisms, including plants. The choice of the precise nucleotide …

Japanese encephalitis virus (JEV) is a mosquito-borne zoonotic flavivirus that causes
encephalitis and reproductive disorders in mammalian species. However, the host factors …

Synthetic biology is a field of scientific research that applies engineering principles to living
organisms and living systems. It is a field that is increasing in scope with respect to …

Viruses threaten humans, livestock, and plants, and are difficult to combat. Imaging of
viruses by light microscopy is key to uncover the nature of known and emerging viruses in …

Over the decades, rapid nucleic acid detection has been difficult for scientists, especially in
microbiology, biotechnology and immunology. Most technologies are finite in sensitivity …

Since the discovery of the double helix and the introduction of genetic engineering, the
possibility to develop new strategies to manipulate the genome has fascinated scientists …