Genomics in personalized nutrition: can you “eat for your genes”?
VA Mullins, W Bresette, L Johnstone, B Hallmark… - Nutrients, 2020 - mdpi.com
Genome-wide single nucleotide polymorphism (SNP) data are now quickly and
inexpensively acquired, raising the prospect of creating personalized dietary …
inexpensively acquired, raising the prospect of creating personalized dietary …
FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Objective To assess the effect of the FTO genotype on weight loss after dietary, physical
activity, or drug based interventions in randomised controlled trials. Design Systematic …
activity, or drug based interventions in randomised controlled trials. Design Systematic …
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
Aims/hypothesis FTO harbours the strongest known obesity-susceptibility locus in
Europeans. While there is growing evidence for a role for FTO in obesity risk in Asians, its …
Europeans. While there is growing evidence for a role for FTO in obesity risk in Asians, its …
Association between Common Polymorphism near the MC4R Gene and Obesity Risk: A Systematic Review and Meta-Analysis
B Xi, GR Chandak, Y Shen, Q Wang, D Zhou - 2012 - journals.plos.org
Background Genome-wide association studies on Europeans have shown that two
polymorphisms (rs17782313, rs12970134) near the melanocortin 4 receptor (MC4R) gene …
polymorphisms (rs17782313, rs12970134) near the melanocortin 4 receptor (MC4R) gene …
Adolescent maturational transitions in the prefrontal cortex and dopamine signaling as a risk factor for the development of obesity and high fat/high sugar diet induced …
AC Reichelt - Frontiers in behavioral neuroscience, 2016 - frontiersin.org
Adolescence poses as both a transitional period in neurodevelopment and lifestyle
practices. In particular, the developmental trajectory of the prefrontal cortex (PFC), a critical …
practices. In particular, the developmental trajectory of the prefrontal cortex (PFC), a critical …
Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the …
C Ortega-Azorín, JV Sorlí, EM Asensio, O Coltell… - Cardiovascular …, 2012 - Springer
Abstract Background Although the Fat Mass and Obesity (FTO) and Melanocortin-4
Receptor (MC4R) genes have been consistently associated with obesity risk, the association …
Receptor (MC4R) genes have been consistently associated with obesity risk, the association …
Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis
J Eriksson, R Haring, N Grarup, L Vandenput… - PloS one, 2017 - journals.plos.org
Context Obesity in men is associated with low serum testosterone and both are associated
with several diseases and increased mortality. Objectives Examine the direction and …
with several diseases and increased mortality. Objectives Examine the direction and …
Bioactive dietary components—Anti‐obesity effects related to energy metabolism and inflammation
Obesity is the result of the long‐term energy imbalance between the excess calories
consumed and the few calories expended. Reducing the intake of energy dense foods (fats …
consumed and the few calories expended. Reducing the intake of energy dense foods (fats …
Interaction between genes involved in energy intake regulation and diet in obesity
L Crovesy, EL Rosado - Nutrition, 2019 - Elsevier
Obesity is a multifactorial, complex, and public health problem worldwide. Interaction
between genes and environment as associated with diet may predispose an individual to …
between genes and environment as associated with diet may predispose an individual to …
Serum uric acid and adiposity: deciphering causality using a bidirectional Mendelian randomization approach
Background Although the relationship between serum uric acid (SUA) and adiposity is well
established, the direction of the causality is still unclear in the presence of conflicting …
established, the direction of the causality is still unclear in the presence of conflicting …