Oxidative stress in healthy and pathological red blood cells

F Orrico, S Laurance, AC Lopez, SD Lefevre… - Biomolecules, 2023 - mdpi.com
Red cell diseases encompass a group of inherited or acquired erythrocyte disorders that
affect the structure, function, or production of red blood cells (RBCs). These disorders can …

Red blood cell pH, the Bohr effect, and other oxygenation‐linked phenomena in blood O2 and CO2 transport

FB Jensen - Acta Physiologica Scandinavica, 2004 - Wiley Online Library
The discovery of the S‐shaped O2 equilibrium curve and the Bohr effect in 1904 stimulated
a fertile and continued research into respiratory functions of blood and allosteric …

Crystal structure of the anion exchanger domain of human erythrocyte band 3

T Arakawa, T Kobayashi-Yurugi, Y Alguel, H Iwanari… - Science, 2015 - science.org
Anion exchanger 1 (AE1), also known as band 3 or SLC4A1, plays a key role in the removal
of carbon dioxide from tissues by facilitating the exchange of chloride and bicarbonate …

Export by red blood cells of nitric oxide bioactivity

JR Pawloski, DT Hess, JS Stamler - Nature, 2001 - nature.com
Previous studies support a model in which the physiological O2 gradient is transduced by
haemoglobin into the coordinate release from red blood cells of O2 and nitric oxide (NO) …

[图书][B] The structure of biological membranes

PL Yeagle - 2004 - taylorfrancis.com
Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane

ME Campanella, H Chu… - Proceedings of the …, 2005 - National Acad Sciences
To characterize the location of glycolytic enzymes (GEs) in intact human erythrocytes, freshly
drawn blood was fixed and stained with Abs to GAPDH, aldolase, phosphofructokinase …

Mechanisms tagging senescent red blood cells for clearance in healthy humans

HU Lutz, A Bogdanova - Frontiers in physiology, 2013 - frontiersin.org
This review focuses on the analysis and evaluation of the diverse senescence markers
suggested to prime red blood cells (RBC) for clearance in humans. These tags develop in …

Protons, osmolytes, and fitness of internal milieu for protein function

GN Somero - American Journal of Physiology-Regulatory …, 1986 - journals.physiology.org
The composition of the intracellular milieu shows striking similarities among widely different
species. Only certain values of intracellular pH, values that generally reflect alphastat …

Oxygen transport by hemoglobin

H Mairbäurl, RE Weber - Comprehensive physiology, 2011 - Wiley Online Library
Hemoglobin (Hb) constitutes a vital link between ambient O2 availability and aerobic
metabolism by transporting oxygen (O2) from the respiratory surfaces of the lungs or gills to …

A genetic approach to analyzing membrane protein topology

C Manoil, J Beckwith - Science, 1986 - science.org
Fusions of the secreted protein alkaline phosphatase to an integral cytoplasmic membrane
protein of Escherichia coli showed different activities depending on where in the membrane …