HIV and ischemic heart disease

A Vachiat, K McCutcheon, N Tsabedze… - Journal of the American …, 2017 - jacc.org
The association of coronary heart disease (CHD) and human immunodeficiency virus (HIV)
infection has been well recognized for many years. The etiology of the increased prevalence …

[HTML][HTML] Dyslipidemia in dermatological disorders

C Shenoy, MM Shenoy, GK Rao - North American journal of …, 2015 - ncbi.nlm.nih.gov
Dyslipidemias are one of the common metabolic disorders. A link between dermatological
disorders like psoriasis and dyslipidemia has been established in the recent past. Many …

Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis

T Gwag, Z Meng, Y Sui, RN Helsley, SH Park… - Journal of …, 2019 - Elsevier
Background & Aims The most prescribed non-nucleoside reverse transcriptase inhibitor,
efavirenz, has been associated with elevated risk of dyslipidemia and hepatic steatosis in …

Atazanavir is not associated with an increased risk of cardio or cerebrovascular disease events

AA Monforte, P Reiss, L Ryom, W El-Sadr, F Dabis… - Aids, 2013 - journals.lww.com
Objective: To investigate whether there is any association between exposure to atazanavir
(ATV), either when boosted or unboosted by ritonavir, and myocardial infarction (MI) or …

Activation of pregnane X receptor induces atherogenic lipids and PCSK9 by a SREBP2‐mediated mechanism

M Karpale, AJ Käräjämäki, O Kummu… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Many drugs and environmental contaminants induce
hypercholesterolemia and promote the risk of atherosclerotic cardiovascular disease. We …

Prevalence of dyslipidaemia among HIV-infected patients receiving combination antiretroviral therapy in North Shewa, Ethiopia

T Fiseha, W Alemu, H Dereje, Z Tamir, A Gebreweld - PloS one, 2021 - journals.plos.org
Background Data on the burden of dyslipidaemia among people with HIV undergoing
antiretroviral therapy (ART) in sub-Saharan Africa are limited and little is known about the …

Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window

JL Sloane, NL Benner, KN Keenan… - Proceedings of the …, 2020 - National Acad Sciences
AIDS is a pandemic disease caused by HIV that affects 37 million people worldwide. Current
antiretroviral therapy slows disease progression but does not eliminate latently infected …

Liver fibrosis in HIV: which role does HIV itself, long-term drug toxicities and metabolic changes play?

JK Rockstroh, R Mohr, G Behrens… - Current Opinion in HIV …, 2014 - journals.lww.com
Therefore, aging of the liver in HIV may play a much more pivotal role in the future
considering age-related effects, coinfection with hepatotropic viruses and the toxicity of long …

Altered lipidome composition is related to markers of monocyte and immune activation in antiretroviral therapy treated human immunodeficiency virus (HIV) infection …

ER Bowman, M Kulkarni, J Gabriel, MJ Cichon… - Frontiers in …, 2019 - frontiersin.org
Background: HIV infection and antiretroviral therapy (ART) have both been linked to
dyslipidemia and increased cardiovascular disease (CVD) risk. Alterations in the …

HIV and metabolic, body, and bone disorders: what we know from low-and middle-income countries

MK Ali, MJ Magee, JA Dave, I Ofotokun… - JAIDS Journal of …, 2014 - journals.lww.com
Globally, the HIV epidemic is evolving. Life expectancy for HIV-infected individuals has been
extended because of more effective and more widely available antiretroviral therapy. As a …