The gut microbiome and hypertension
A large body of evidence has emerged in the past decade supporting a role for the gut
microbiome in the regulation of blood pressure. The field has moved from association to …
microbiome in the regulation of blood pressure. The field has moved from association to …
Importance of gut microbiota metabolites in the development of cardiovascular diseases (CVD)
M Hemmati, S Kashanipoor, P Mazaheri, F Alibabaei… - Life Sciences, 2023 - Elsevier
Cardiovascular disease (CVD) remains the most common cause of death worldwide and
has become a public health concern. The proven notable risk factors for CVD are …
has become a public health concern. The proven notable risk factors for CVD are …
Gut microbiota-generated phenylacetylglutamine and heart failure
KA Romano, I Nemet, P Prasad Saha… - Circulation: Heart …, 2023 - Am Heart Assoc
Background: The gut microbiota-dependent metabolite phenylacetylgutamine (PAGln) is
both associated with atherothrombotic heart disease in humans, and mechanistically linked …
both associated with atherothrombotic heart disease in humans, and mechanistically linked …
[HTML][HTML] The implication of the gut microbiome in heart failure
VV Lupu, A Adam Raileanu, CM Mihai, ID Morariu… - Cells, 2023 - mdpi.com
Heart failure is a worldwide health problem with important consequences for the overall
wellbeing of affected individuals as well as for the healthcare system. Over recent decades …
wellbeing of affected individuals as well as for the healthcare system. Over recent decades …
[HTML][HTML] Prebiotic intervention with HAMSAB in untreated essential hypertensive patients assessed in a phase II randomized trial
Fibers remain undigested until they reach the colon, where some are fermented by gut
microbiota, producing metabolites called short-chain fatty acids (SCFAs), such as acetate …
microbiota, producing metabolites called short-chain fatty acids (SCFAs), such as acetate …
Cardiac metabolism in HFpEF: from fuel to signalling
Heart failure (HF) is marked by distinctive changes in myocardial uptake and utilization of
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
energy substrates. Among the different types of HF, HF with preserved ejection fraction …
[HTML][HTML] Metformin and the heart: update on mechanisms of cardiovascular protection with special reference to comorbid type 2 diabetes and heart failure
G Schernthaner, K Brand, CJ Bailey - Metabolism, 2022 - Elsevier
Metformin has been in clinical use for the management of type 2 diabetes for more than 60
years and is supported by a vast database of clinical experience: this includes evidence for …
years and is supported by a vast database of clinical experience: this includes evidence for …
Essential hypertension is associated with changes in gut microbial metabolic pathways: a multisite analysis of ambulatory blood pressure
Recent evidence supports a role for the gut microbiota in hypertension, but whether
ambulatory blood pressure is associated with gut microbiota and their metabolites remains …
ambulatory blood pressure is associated with gut microbiota and their metabolites remains …
Gut microbiota and microbial metabolism in early risk of cardiometabolic disease
CL Gabriel, JF Ferguson - Circulation Research, 2023 - Am Heart Assoc
Cardiometabolic disease comprises cardiovascular and metabolic dysfunction and
underlies the leading causes of morbidity and mortality, both within the United States and …
underlies the leading causes of morbidity and mortality, both within the United States and …
Causal relationships between the gut microbiome, blood lipids, and heart failure: a Mendelian randomization analysis
Aims Studies have linked gut microbiome and heart failure (HF). However, their causal
relationships and potential mediating factors have not been well defined. To investigate the …
relationships and potential mediating factors have not been well defined. To investigate the …