Freshwater planarians, Plathelminthes, have been an intriguing model animal of
regeneration studies for more than 100 years. Their robust regenerative ability is one of …

Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …

INTRODUCTION The complete sequence of animal genomes has had a transformative
impact on biological research. Whereas the genome sequence of an organism contains the …

Planarians can regenerate any missing body part in a process requiring dividing cells called
neoblasts. Historically, neoblasts have largely been considered a homogeneous stem cell …

Among the millions of invertebrate species with visual systems, the genetic basis of eye
development and function is well understood only in Drosophila melanogaster. We describe …

In contrast to most adult organisms, freshwater planarians can regenerate any injured body
part, including their entire nervous system. This allows for the analysis of genes required for …

The regenerative capabilities of freshwater planarians (Platyhelminthes) are very difficult to
match. A fragment as tiny as 1/279th of the planarian body is able to regenerate a whole …

Background Planarian flatworms can regenerate their head, including a functional brain,
within less than a week. Despite the enormous potential of these animals for medical …

Similarly to development, the process of regeneration requires that cells accurately sense
and respond to their external environment. Thus, intrinsic cues must be integrated with …

Planarians are the simplest animals to exhibit a body plan common to all vertebrates and
many invertebrates, characterized by bilateral rather than radial symmetry, dorsal and …