Only 25% of multidrug-resistant tuberculosis (MDR-TB) cases are currently diagnosed. Line
probe assays (LPAs) enable rapid drug-susceptibility testing for rifampicin (RIF) and …

Introduction: Tuberculosis remains a global health problem and pharmacokinetic variability
has been postulated as one of the causes of treatment failure and acquired drug resistance …

OBJECTIVE: To present a global update of drug-resistant tuberculosis (TB) and explore
trends in 1994-2010. METHODS: Data on drug resistance among new and previously …

Background There is an urgent demand for rapid and accurate drug-susceptibility testing for
the detection of multidrug-resistant tuberculosis. The GenoType MTBDR plus assay is a …

SETTING: The first national anti-tuberculosis drug resistance survey in Pakistan, a high
tuberculosis (TB) and low human immunodeficiency virus (HIV) burden country …

GenoType MTBDRplus is a molecular assay for detection of Mycobacterium tuberculosis
and drug resistance. Assay performance as applied directly to consecutive unselected …

Tuberculosis (TB) is the most common opportunistic infection in human immunodeficiency
virus (HIV)-infected patients and the emergence of drug-resistant tuberculosis (DR-TB) is a …

Abstract Background Line probe assays (LPAs) are PCR-based assays used for the rapid
diagnosis of Mycobacterium tuberculosis (MTB) and drug-resistant tuberculosis (DR-TB). But …

Rapid identification of drug resistance in clinical isolates of Mycobacterium tuberculosis is
important in determining treatment for tuberculosis. The aim of this work was evaluate the …

Objective The prevalence of MDR‐TB in Zambia was estimated to be 1.8% in 2001. A
second drug resistance survey was conducted in 2008 to determine trends; the use of the …