The role and therapeutic potential of exosomes in ischemic stroke

JY Li, QQ Li, R Sheng - Neurochemistry International, 2021 - Elsevier
Ischemic stroke is a disease caused by insufficient blood and oxygen supply to the brain,
which is mainly due to intracranial arterial stenosis and middle cerebral artery occlusion …

Role of autophagy and transcriptome regulation in acute brain injury

V Arruri, R Vemuganti - Experimental neurology, 2022 - Elsevier
Autophagy is an evolutionarily conserved intracellular system that routes distinct cytoplasmic
cargo to lysosomes for degradation and recycling. Accumulating evidence highlight the …

Circ-0000953 deficiency exacerbates podocyte injury and autophagy disorder by targeting Mir665-3p-Atg4b in diabetic nephropathy

X Liu, L Jiang, H Zeng, L Gao, S Guo, C Chen, X Liu… - Autophagy, 2024 - Taylor & Francis
Circular RNAs (circRNAs) are special non-coding RNA (ncRNA) molecules that play a
significant role in many diseases. However, the biogenesis and regulation of circRNAs in …

[HTML][HTML] CircUBE2Q2 promotes differentiation of cattle muscle stem cells and is a potential regulatory molecule of skeletal muscle development

RM Zhang, Y Pan, CX Zou, Q An, JR Cheng, PJ Li… - BMC genomics, 2022 - Springer
Background The growth and development of muscle stem cells (MuSCs) are significant
events known to affect muscle plasticity, disease, meat production, and meat quality, which …

circNup188/miR-760–3p/Map3k8 axis regulates inflammation in cerebral ischemia

H Zhang, J Deng, K Huang, Y He, Z Cai, Y He - Molecular and cellular …, 2022 - Elsevier
Introduction Cerebral ischemia is a serious acute disease with high mortality and disability
rates. circRNAs are associated with cerebral ischemia inflammation and can be used as …

ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5

J Yang, S Peng, K Zhang - Human & Experimental …, 2022 - journals.sagepub.com
Increasing studies indicate that cholesterol plays an important role in drug resistance.
ARL4C is implicated in the export and import of cholesterol, therefore this study aimed to …

[HTML][HTML] The LMCD1-AS1/miR-526b-3p/OSBPL5 axis promotes cell proliferation, migration and invasion in non-small cell lung cancer

R Hu, Y Yu, H Wang - BMC Pulmonary Medicine, 2022 - Springer
Purpose To explore the specific role and regulatory mechanism of oxysterol binding protein
like 5 (OSBPL5) in non-small cell lung cancer (NSCLC). Methods and results Quantitative …

[HTML][HTML] Proteomics and Its Combined Analysis with Transcriptomics: Liver Fat-Lowering Effect of Taurine in High-Fat Fed Grouper (Epinephelus coioides)

Y Zhou, F Bai, R Xiao, M Chen, Y Sun, J Ye - Animals, 2024 - mdpi.com
Simple Summary Taurine has a wide range of biological functions in vertebrates but does
not participate in protein synthesis. Recent studies showed taurine exhibits an important role …

[HTML][HTML] Redox signaling and cardiovascular disease: New paradigms and discoveries

Y Chen, CG Kevil - Redox Biology, 2020 - ncbi.nlm.nih.gov
Discoveries of Nobel laureate Prof Albert Szent-Györgyi regarding vitamin C and catalysis of
fumaric acid are perhaps some of the earliest foundations of redox signaling providing a …

Stress conditions induced circRNAs profile of extracellular vesicles in brain microvascular endothelial cells

XL Min, H Zou, J Yan, Q Lyu, X He, FF Shang - Metabolic Brain Disease, 2022 - Springer
Cerebral ischemia causes hypoxic injury and inflammation, and brain microvascular
endothelial cells (BMVECs) dysfunction is an initial stage of blood-brain barrier disruption …