[HTML][HTML] Onion (Allium cepa L.) peels: A review on bioactive compounds and biomedical activities
Huge quantities of byproducts/wastes generated in onion processing are usually discarded,
but they are excellent sources of bioactive compounds and phytochemicals. However, with …
but they are excellent sources of bioactive compounds and phytochemicals. However, with …
Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …
Neuropharmacological effects of quercetin: a literature-based review
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …
beneficial properties in many pathologies. Its neuroprotective effects have been …
Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases
Complex diseases such as neurodegenerative disorders and cancer constitute a growing
public health problem due to the rising incidence and lack in effective therapies. Since …
public health problem due to the rising incidence and lack in effective therapies. Since …
Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer's disease
Abstract Chalcone [(E)-1, 3-diphenyl-2-propene-1-one], a small molecule with α, β
unsaturated carbonyl group is a precursor or component of many natural flavonoids and …
unsaturated carbonyl group is a precursor or component of many natural flavonoids and …
Role of prenatal hypoxia in brain development, cognitive functions, and neurodegeneration
NN Nalivaeva, AJ Turner, IA Zhuravin - Frontiers in neuroscience, 2018 - frontiersin.org
This review focuses on the role of prenatal hypoxia in the development of brain functions in
the postnatal period and subsequent increased risk of neurodegenerative disorders in later …
the postnatal period and subsequent increased risk of neurodegenerative disorders in later …
Status of acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease and type 2 diabetes mellitus
Both Alzheimer's disease (AD) and Type 2 diabetes mellitus (T2DM) share the presence of
systemic and neuro-inflammation, enhanced production and accumulation of β-amyloid …
systemic and neuro-inflammation, enhanced production and accumulation of β-amyloid …
Recent advances in enzyme-activated NIR fluorescent probes for biological applications
Enzymes and their regulations are employed as indicators for various diseases, including
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …
cancer. To directly analyze the activity of the enzymes within a biological system, enzyme …
Sustainable drug discovery of multi-target-directed ligands for Alzheimer's disease
M Rossi, M Freschi… - Journal of medicinal …, 2021 - ACS Publications
The multifactorial nature of Alzheimer's disease (AD) is a reason for the lack of effective
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …
Combined computational approaches for developing new anti-Alzheimer drug candidates: 3D-QSAR, molecular docking and molecular dynamics studies of …
Butyrylcholinesterase is an acetylcholine-degrading enzyme involved in the memorization
process, which is becoming an interesting target for the symptomatic treatment of …
process, which is becoming an interesting target for the symptomatic treatment of …