To adequately prepare for potential hazards caused by emerging and reemerging infectious
diseases, the WHO has issued a list of high-priority pathogens that are likely to cause future …

The persistence of SARS-CoV-2 infections at a global level reflects the repeated emergence
of variant strains encoding unique constellations of mutations. These variants have been …

SARS-CoV-2 variants are mainly defined by mutations in their spike. It is therefore critical to
understand how the evolutionary trajectories of spike affect virus phenotypes. So far, it has …

Human coronavirus (CoV) HKU1 infection typically causes common cold but can lead to
pneumonia in children, older people, and immunosuppressed individuals. Recently, human …

Subversion of cellular membranes and membrane proliferation are used by positive-strand
RNA viruses to build viral replication organelles (VROs) that support virus replication. The …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic caused the
biggest public health crises in recent history. Many expect future coronavirus introductions …

Ras-GTPase-activating protein SH3-domain-binding proteins (G3BP) are critical for the
formation of stress granules (SGs) through their RNA-and ribosome-binding properties …

High-throughput experiments often produce ranked gene outputs, with forward genetic
screening being a notable example. While there are various tools for analyzing individual …

Non-structural protein 1 (Nsp1) is one of the first proteins produced during coronaviral
infections. It plays a pivotal role in hijacking and rendering the host gene expression under …

Summary Background Although several SARS-CoV-2-related coronaviruses (SC2r-CoVs)
were discovered in bats and pangolins, the differences in virological characteristics between …