Serial femtosecond crystallography

TRM Barends, B Stauch, V Cherezov… - Nature reviews Methods …, 2022 - nature.com
With the advent of X-ray free-electron lasers (XFELs), new, high-throughput serial
crystallography techniques for macromolecular structure determination have emerged …

Bacterial toxins active against mosquitoes: Mode of action and resistance

MHNL Silva-Filha, TP Romão, TMT Rezende… - Toxins, 2021 - mdpi.com
Larvicides based on the bacteria Bacillus thuringiensis svar. israelensis (Bti) and
Lysinibacillus sphaericus are effective and environmentally safe compounds for the control …

Structural insights into functional properties of the oxidized form of cytochrome c oxidase

I Ishigami, RG Sierra, Z Su, A Peck, C Wang… - Nature …, 2023 - nature.com
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial
respiration. It catalyzes the four-electron reduction of molecular oxygen to water and …

[HTML][HTML] Recent results in time resolved serial femtosecond crystallography at XFELs

AM Orville - Current Opinion in Structural Biology, 2020 - Elsevier
Highlights•Time-resolved serial femtosecond crystallography (tr-SFX) probes structure and
function in each sample.•X-ray free electron lasers (XFELS) provide atomic and electronic …

[HTML][HTML] Environmental and socioeconomic effects of mosquito control in Europe using the biocide Bacillus thuringiensis subsp. israelensis (Bti)

CA Brühl, L Després, O Frör, CD Patil, B Poulin… - Science of the total …, 2020 - Elsevier
Bacillus thuringiensis subsp. israelensis (Bti) has been used in mosquito control programs to
reduce nuisance in Europe for decades and is generally considered an environmentally …

[HTML][HTML] Advances in methods for atomic resolution macromolecular structure determination

MC Thompson, TO Yeates, JA Rodriguez - F1000Research, 2020 - ncbi.nlm.nih.gov
Recent technical advances have dramatically increased the power and scope of structural
biology. New developments in high-resolution cryo-electron microscopy, serial X-ray …

De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals

G Tetreau, MR Sawaya, E De Zitter… - Nature …, 2022 - nature.com
Abstract Cry11Aa and Cry11Ba are the two most potent toxins produced by mosquitocidal
Bacillus thuringiensis subsp. israelensis and jegathesan, respectively. The toxins naturally …

A snapshot love story: what serial crystallography has done and will do for us

A Henkel, D Oberthür - Biological Crystallography, 2024 - journals.iucr.org
Serial crystallography, born from groundbreaking experiments at the Linac Coherent Light
Source in 2009, has evolved into a pivotal technique in structural biology. Initially pioneered …

Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook

S Botha, P Fromme - Structure, 2023 - cell.com
Serial femtosecond crystallography (SFX) revolutionized macromolecular crystallography
over the past decade by enabling the collection of X-ray diffraction data from nano-or …

[PDF][PDF] Going around the Kok cycle of the water oxidation reaction with femtosecond X-ray crystallography

A Bhowmick, PS Simon, I Bogacz, R Hussein, M Zhang… - IUCrJ, 2023 - journals.iucr.org
The water oxidation reaction in photosystem II (PS II) produces most of the molecular oxygen
in the atmosphere, which sustains life on Earth, and in this process releases four electrons …