The human genome encodes probably more than 20 different sialyltransferases involved in
the biosynthesis of sialylated glycoproteins and glycolipids but to date only 15 different …

One of the major advantages of the baculovirus-insect cell system is that it is a eukaryotic
system that can provide posttranslational modifications, such as protein N-glycosylation …

The animal sialyltransferases are Golgi type II transmembrane glycosyltransferases. Twenty
distinct sialyltransferases have been identified in both human and murine genomes. These …

On the basis of function and sequence similarities, the vertebrate fucosyltransferases can be
classified into three groups: α-2-, α-3-, and α-6-fucosyltransferases. Thirty new putative …

Polysialic acid is a unique cell surface polysaccharide found in the capsule of neuroinvasive
bacteria and as a highly regulated post-translational modification of the neural cell adhesion …

Glycosyltransferases are the enzymes that synthesize oligosaccharides, polysaccharides
and glycoconjugates. The analysis of the wealth of sequences that are now available in …

Sialyltransferases (STs) represent an important group of enzymes that transfer N-
acetylneuraminic acid (Neu5Ac) from cytidine monophosphate-Neu5Ac to various acceptor …

Polysialic acid (polySia) is a carbohydrate polymer critical for neuronal cell migration and
axon pathfinding in embryonic development. Besides brain regions requiring persistent …

Sialic acid is the most abundant terminal monosaccharide on mammalian cell surface
glycoconjugates. The crystal structures of a mammalian sialyltransferase, that of porcine …

A novel member of the human β-galactoside α2, 6-sialyltransferase (ST6Gal) family,
designated ST6Gal II, was identified by BLAST analysis of expressed sequence tags and …