Advances in Spheroids and Organoids on a Chip
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …
medicine and drug screening. They replicate the structural and functional characteristics of …
Acoustic microfluidics
Acoustic microfluidic devices are powerful tools that use sound waves to manipulate micro-
or nanoscale objects or fluids in analytical chemistry and biomedicine. Their simple device …
or nanoscale objects or fluids in analytical chemistry and biomedicine. Their simple device …
Advances in multicellular spheroids formation
Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
Engineering multi‐cellular spheroids for tissue engineering and regenerative medicine
Multi‐cellular spheroids are formed as a 3D structure with dense cell–cell/cell–extracellular
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …
The synergy of scaffold-based and scaffold-free tissue engineering strategies
A Ovsianikov, A Khademhosseini, V Mironov - Trends in biotechnology, 2018 - cell.com
Tissue engineering (TE) is a highly interdisciplinary research field driven by the goal to
restore, replace, or regenerate defective tissues. Throughout more than two decades of …
restore, replace, or regenerate defective tissues. Throughout more than two decades of …
Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …
provide similar metabolism, proliferation, and species concentration gradients to those found …
Three‐dimensional multicellular biomaterial platforms for biomedical application
J Hao, C Qin, C Wu - Interdisciplinary Materials, 2023 - Wiley Online Library
Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …
biomaterials have been widely applied in biomedical fields for the regeneration of complex …
[HTML][HTML] The tumor-on-chip: Recent advances in the development of microfluidic systems to recapitulate the physiology of solid tumors
G Trujillo-de Santiago, BG Flores-Garza… - Materials, 2019 - mdpi.com
The ideal in vitro recreation of the micro-tumor niche—although much needed for a better
understanding of cancer etiology and development of better anticancer therapies—is highly …
understanding of cancer etiology and development of better anticancer therapies—is highly …
[HTML][HTML] Neutrophil-inspired propulsion in a combined acoustic and magnetic field
Abstract Systems capable of precise motion in the vasculature can offer exciting possibilities
for applications in targeted therapeutics and non-invasive surgery. So far, the majority of the …
for applications in targeted therapeutics and non-invasive surgery. So far, the majority of the …
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications
MC Decarli, R Amaral, DP Dos Santos, LB Tofani… - …, 2021 - iopscience.iop.org
Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …