Surveying membrane landscapes: a new look at the bacterial cell surface
Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …
Outer membrane porins contribute to antimicrobial resistance in gram-negative bacteria
Gram-negative bacteria depend on their cell membranes for survival and environmental
adaptation. They contain two membranes, one of which is the outer membrane (OM), which …
adaptation. They contain two membranes, one of which is the outer membrane (OM), which …
A periplasmic phospholipase that maintains outer membrane lipid asymmetry in Pseudomonas aeruginosa
RL Guest, MJ Lee, W Wang… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane of Gram-negative bacteria is unique in both structure and function. The
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …
surface-exposed outer leaflet is composed of lipopolysaccharide, while the inner leaflet is …
Darobactin B Stabilises a Lateral‐Closed Conformation of the BAM Complex in E. coli Cells
SF Haysom, J Machin, JM Whitehouse… - Angewandte Chemie …, 2023 - Wiley Online Library
The β‐barrel assembly machinery (BAM complex) is essential for outer membrane protein
(OMP) folding in Gram‐negative bacteria, and represents a promising antimicrobial target …
(OMP) folding in Gram‐negative bacteria, and represents a promising antimicrobial target …
Tunable force transduction through the Escherichia coli cell envelope
DP Williams-Jones, MN Webby… - Proceedings of the …, 2023 - National Acad Sciences
The outer membrane (OM) of Gram-negative bacteria is not energised and so processes
requiring a driving force must connect to energy-transduction systems in the inner …
requiring a driving force must connect to energy-transduction systems in the inner …
Mechanism of outer membrane destabilization by global reduction of protein content
The outer membrane (OM) of Gram-negative bacteria such as Escherichia coli is an
asymmetric bilayer with the glycolipid lipopolysaccharide (LPS) in the outer leaflet and …
asymmetric bilayer with the glycolipid lipopolysaccharide (LPS) in the outer leaflet and …
Molecular Machines that Facilitate Bacterial Outer Membrane Protein Biogenesis
MT Doyle, HD Bernstein - Annual Review of Biochemistry, 2024 - annualreviews.org
Almost all outer membrane proteins (OMPs) in Gram-negative bacteria contain a β-barrel
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
domain that spans the outer membrane (OM). To reach the OM, OMPs must be translocated …
A dual detergent strategy to capture a bacterial outer membrane proteome in peptidiscs for characterization by mass spectrometry and binding assays
The outer membrane of Gram-negative bacteria plays a critical role in protecting the cell
against external stressors, including antibiotics, and therefore is a prime target for …
against external stressors, including antibiotics, and therefore is a prime target for …
[HTML][HTML] Computational microbiology of bacteria: Advancements in molecular dynamics simulations
Microbiology is traditionally considered within the context of wet laboratory methodologies.
Computational techniques have a great potential to contribute to microbiology. Here, we …
Computational techniques have a great potential to contribute to microbiology. Here, we …
Reply to: Antibiotics and hexagonal order in the bacterial outer membrane
Methods AFM imaging and analysis OMVs produced from different E. coli MG1655 strains
were adsorbed onto freshly cleaved mica for 15min in DPBS buffer at room temperature …
were adsorbed onto freshly cleaved mica for 15min in DPBS buffer at room temperature …