Fundamentals of hdx-ms
V Vinciauskaite, GR Masson - Essays in Biochemistry, 2023 - portlandpress.com
Hydrogen deuterium exchange mass spectrometry (HDX-MS) is becoming part of the
standard repertoire of techniques used by molecular biologists to investigate protein …
standard repertoire of techniques used by molecular biologists to investigate protein …
Alphavirus RNA replication in vertebrate cells
T Ahola, G McInerney, A Merits - Advances in virus research, 2021 - Elsevier
Alphaviruses are positive-strand RNA viruses, typically transmitted by mosquitoes between
vertebrate hosts. They encode four essential replication proteins, the non-structural proteins …
vertebrate hosts. They encode four essential replication proteins, the non-structural proteins …
Molecular architecture of the Chikungunya virus replication complex
To better understand how positive-strand (+) RNA viruses assemble membrane-associated
replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected …
replication complexes (RCs) to synthesize, process, and transport viral RNA in virus-infected …
Architecture of the chikungunya virus replication organelle
T Laurent, P Kumar, S Liese, F Zare, M Jonasson… - Elife, 2022 - elifesciences.org
Alphaviruses are mosquito-borne viruses that cause serious disease in humans and other
mammals. Along with its mosquito vector, the Alphavirus chikungunya virus (CHIKV) has …
mammals. Along with its mosquito vector, the Alphavirus chikungunya virus (CHIKV) has …
Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching
H Zhan, N Unchwaniwala… - Proceedings of the …, 2023 - National Acad Sciences
Positive-strand RNA viruses replicate their genomes in virus-induced membrane vesicles,
and the resulting RNA replication complexes are a major target for virus control. Nodavirus …
and the resulting RNA replication complexes are a major target for virus control. Nodavirus …
[HTML][HTML] De novo modelling of HEV replication polyprotein: Five-domain breakdown and involvement of flexibility in functional regulation
S Fieulaine, T Tubiana, S Bressanelli - Virology, 2023 - Elsevier
Hepatitis E virus (HEV), a major cause of acute viral hepatitis, is a single-stranded, positive-
sense RNA virus. As such, it encodes a 1700-residue replication polyprotein pORF1 that …
sense RNA virus. As such, it encodes a 1700-residue replication polyprotein pORF1 that …
[HTML][HTML] The life cycle of the alphaviruses: From an antiviral perspective
AM Skidmore, SB Bradfute - Antiviral research, 2023 - Elsevier
The alphaviruses are a widely distributed group of positive-sense, single stranded, RNA
viruses. These viruses are largely arthropod-borne and can be found on all populated …
viruses. These viruses are largely arthropod-borne and can be found on all populated …
Drugs targeting structural and nonstructural proteins of the chikungunya virus: A review
M Wang, L Wang, P Leng, J Guo, H Zhou - International Journal of …, 2024 - Elsevier
Chikungunya virus (CHIKV) is a single positive-stranded RNA virus of the Togaviridae family
and Alphavirus genus, with a typical lipid bilayer envelope structure, and is the causative …
and Alphavirus genus, with a typical lipid bilayer envelope structure, and is the causative …
The 8-bromobaicalein alleviated chikungunya-induced musculoskeletal inflammation and reduced the viral load in healthy adult mice
V Cao, N Loeanurit, K Hengphasatporn… - Emerging Microbes & …, 2023 - Taylor & Francis
Chikungunya virus is a re-emerging arbovirus that has caused epidemic outbreaks in recent
decades. Patients in older age groups with high viral load and severe immunologic …
decades. Patients in older age groups with high viral load and severe immunologic …
Inhibitors of the Structural and Nonstructural Proteins of Alphaviruses
DS Metibemu, OS Adeyinka, J Falode… - ACS Infectious …, 2024 - ACS Publications
The Alphavirus genus includes viruses that cause encephalitis due to neuroinvasion and
viruses that cause arthritis due to acute and chronic inflammation. There is no approved …
viruses that cause arthritis due to acute and chronic inflammation. There is no approved …