Long-term survival after kidney transplantation
S Hariharan, AK Israni… - New England Journal of …, 2021 - Mass Medical Soc
Long-Term Survival after Kidney Transplantation This review discusses demographics,
survival, and risks in kidney transplantation since the mid-1990s. It addresses postoperative …
survival, and risks in kidney transplantation since the mid-1990s. It addresses postoperative …
The evolving story of apolipoprotein L1 nephropathy: the end of the beginning
P Daneshpajouhnejad, JB Kopp, CA Winkler… - Nature Reviews …, 2022 - nature.com
Genetic coding variants in APOL1, which encodes apolipoprotein L1 (APOL1), were
identified in 2010 and are relatively common among individuals of sub-Saharan African …
identified in 2010 and are relatively common among individuals of sub-Saharan African …
APOL1 nephropathy: from genetics to clinical applications
DJ Friedman, MR Pollak - … Journal of the American Society of …, 2021 - journals.lww.com
Rates of many types of severe kidney disease are much higher in Black individuals than
most other ethnic groups. Much of this disparity can now be attributed to genetic variants in …
most other ethnic groups. Much of this disparity can now be attributed to genetic variants in …
Evaluating the promise of inclusion of African ancestry populations in genomics
AR Bentley, SL Callier, CN Rotimi - NPJ genomic medicine, 2020 - nature.com
The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …
known, and the resultant scientific and ethical limitations are becoming increasingly …
[HTML][HTML] Genetic evaluation of living kidney donor candidates: a review and recommendations for best practices
The growing accessibility and falling costs of genetic sequencing techniques has expanded
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …
the utilization of genetic testing in clinical practice. For living kidney donation, genetic …
[HTML][HTML] APOL1 long-term kidney transplantation outcomes network (APOLLO): design and rationale
BI Freedman, MM Moxey-Mims, AA Alexander… - Kidney international …, 2020 - Elsevier
Introduction Much of the higher risk for end-stage kidney disease (ESKD) in African
American individuals relates to ancestry-specific variation in the apolipoprotein L1 gene …
American individuals relates to ancestry-specific variation in the apolipoprotein L1 gene …
Kidney disease and APOL1
AA Yusuf, MA Govender… - Human Molecular …, 2021 - academic.oup.com
Globally, chronic kidney disease (CKD) represents an important non-communicable disease
with significant morbidity and mortality. An estimated 10% of the world's population had CKD …
with significant morbidity and mortality. An estimated 10% of the world's population had CKD …
APOL1 and Kidney Disease: From Genetics to Biology
DJ Friedman, MR Pollak - Annual review of physiology, 2020 - annualreviews.org
Genetic variants in the APOL1 gene, found only in individuals of recent African ancestry,
greatly increase risk of multiple types of kidney disease. These APOL1 kidney risk alleles …
greatly increase risk of multiple types of kidney disease. These APOL1 kidney risk alleles …
Recent advances and clinical outcomes of kidney transplantation
Recent advances in surgical, immunosuppressive and monitoring protocols have led to the
significant improvement of overall one-year kidney allograft outcomes. Nonetheless, there …
significant improvement of overall one-year kidney allograft outcomes. Nonetheless, there …
A SNARE protective pool antagonizes APOL1 renal toxicity in Drosophila nephrocytes
Abstract Background People of Sub-Saharan African ancestry are at higher risk of
developing chronic kidney disease (CKD), attributed to the Apolipoprotein L1 (APOL1) gene …
developing chronic kidney disease (CKD), attributed to the Apolipoprotein L1 (APOL1) gene …