[HTML][HTML] Future regenerative medicine developments and their therapeutic applications

AE Altyar, A El-Sayed, A Abdeen, M Piscopo… - Biomedicine & …, 2023 - Elsevier
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

A critical update of the assessment and acute management of patients with severe burns

TC Lang, R Zhao, A Kim, A Wijewardena… - Advances in wound …, 2019 - liebertpub.com
Significance: Burns are debilitating, life threatening, and difficult to assess and manage.
Recent advances in assessment and management have occurred since a comprehensive …

Regenerating dynamic organs using biomimetic patches

P Chansoria, EL Etter, J Nguyen - Trends in biotechnology, 2022 - cell.com
The regeneration of dynamic organs remains challenging because they are intrinsically
anisotropic and undergo large volumetric deformation during normal or pathological …

Cutaneous cell therapy manufacturing timeframe rationalization: allogeneic off-the-freezer fibroblasts for dermo-epidermal combined preparations (DE-FE002-SK2) in …

X Chen, A Laurent, Z Liao, S Jaccoud, P Abdel-Sayed… - Pharmaceutics, 2023 - mdpi.com
Autologous cell therapy manufacturing timeframes constitute bottlenecks in clinical
management pathways of severe burn patients. While effective temporary wound coverings …

[HTML][HTML] Incorporation of silver sulfadiazine into an electrospun composite of polycaprolactone as an antibacterial scaffold for wound healing in rats

F Nejaddehbashi, M Hashemitabar, V Bayati… - Cell Journal …, 2020 - ncbi.nlm.nih.gov
Objective Fabrication of an antibiotic-loaded scaffold with controlled release properties for
wound dressing is one of tissue engineering challenges. The aim of this study was to …

[HTML][HTML] ATMP-classified, scalable, autologous cell spray for the treatment of skin wounds and assessment of its effects on wound healing clinically and on a molecular …

K Nuutila, S Katayama, A Laitinen, A Siltanen… - burns, 2023 - Elsevier
Background Autologous split-thickness skin grafts (STSGs) are the standard of care for
closure of deep and large burns. However, perforation and extensive fishnet-like expansion …

Elastin-like recombinamers in collagen-based tubular gels improve cell-mediated remodeling and viscoelastic properties

DB Camasão, M González-Pérez, S Palladino… - Biomaterials …, 2020 - pubs.rsc.org
Natural polymers are commonly used as scaffolds for vascular tissue engineering. The
recognized biological properties of this class of materials are often counterbalanced by their …

Outcome comparison of the most commonly employed wound coverage techniques in patients with massive burns≥ 50% TBSA–A systematic review and meta …

V Haug, C Tapking, AC Panayi, A Veeramani… - Burns, 2024 - Elsevier
Introduction Early wound coverage is one of the most essential factors influencing the
survival of extensively burned patients, especially those with a total body surface area …

[HTML][HTML] The Wound-Healing Effect of a Novel Fibroblasts-Impregnated Hydroxyethylcellulose Gel in a Rat Full-Thickness Burn Model: A Preclinical Study

YA Novosad, AS Shabunin, NI Enukashvily… - Biomedicines, 2024 - mdpi.com
Background/Objectives: The objective of this study was to assess the efficacy of a cell-
containing wound dressing based on fibroblasts in hydroxyethylcellulose (HEC) gel for the …

Sprayable Bioactive Dressings for Skin Wounds: Recent Developments and Future Prospects

APM Nozaki, MH de Melo Lima, ÂM Moraes - Biomedical Materials & …, 2023 - Springer
The skin, as the body's main protection barrier from the environment, has an intrinsic self-
repairable nature. However, proper wound healing only occurs under appropriate …