The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

FE Poynton, SA Bright, S Blasco, DC Williams… - Chemical Society …, 2017 - pubs.rsc.org
Ruthenium (II)[Ru (II)] polypyridyl complexes have been the focus of intense investigations
since work began exploring their supramolecular interactions with DNA. In recent years …

Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Suppression of Kasha's rule as a mechanism for fluorescent molecular rotors and aggregation-induced emission

H Qian, ME Cousins, EH Horak, A Wakefield… - Nature …, 2017 - nature.com
Although there are some proposed explanations for aggregation-induced emission, a
phenomenon with applications that range from biosensors to organic light-emitting diodes …

Phosphorescent heavy-metal complexes for bioimaging

Q Zhao, C Huang, F Li - Chemical Society Reviews, 2011 - pubs.rsc.org
The application of phosphorescent heavy-metal complexes with d6, d8 and d10 electron
configurations for bioimaging is a new and promising research field and has been attracting …

Ruthenium (II) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

MR Gill, JA Thomas - Chemical Society Reviews, 2012 - pubs.rsc.org
In the last few decades, coordination complexes based on d6 metal centres and polypyridyl
ligand architectures been developed as structure-and site-specific reversible DNA binding …

Strategies for the nuclear delivery of metal complexes to cancer cells

M Huynh, R Vinck, B Gibert, G Gasser - Advanced Materials, 2024 - Wiley Online Library
The nucleus is an essential organelle for the function of cells. It holds most of the genetic
material and plays a crucial role in the regulation of cell growth and proliferation. Since …

Luminescent ruthenium (II) polypyridine complexes for a wide variety of biomolecular and cellular applications

J Shum, PKK Leung, KKW Lo - Inorganic Chemistry, 2019 - ACS Publications
Ruthenium (II) polypyridine complexes are one of the most extensively studied and
developed systems in the family of luminescent transition-metal complexes. Notably, there …

“Chemistry-on-the-complex”: functional Ru II polypyridyl-type sensitizers as divergent building blocks

T Mede, M Jäger, US Schubert - Chemical Society Reviews, 2018 - pubs.rsc.org
Ruthenium polypyridyl type complexes are potent photoactive compounds, and have found–
among others–a broad range of important applications in the fields of biomedical diagnosis …

Ruthenium polypyridyl complex-containing bioconjugates

M Martinez-Alonso, G Gasser - Coordination Chemistry Reviews, 2021 - Elsevier
In the last decades, the number of articles describing the synthesis, characterization and
applications of ruthenium polypyridyl complexes has significantly increased. One of the …