Allergen immunotherapy in children user's guide

M Alvaro‐Lozano, CA Akdis, M Akdis… - Pediatric allergy and …, 2020 - Wiley Online Library
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …

Food allergy: a review and update on epidemiology, pathogenesis, diagnosis, prevention, and management

SH Sicherer, HA Sampson - Journal of Allergy and Clinical Immunology, 2018 - Elsevier
This review provides general information to serve as a primer for those embarking on
understanding food allergy and also details advances and updates in epidemiology …

AR101 oral immunotherapy for peanut allergy

PALISADE Group of Clinical … - New England Journal of …, 2018 - Mass Medical Soc
Background Peanut allergy, for which there are no approved treatment options, affects
patients who are at risk for unpredictable and occasionally life-threatening allergic reactions …

Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety

DK Chu, RA Wood, S French, A Fiocchi, M Jordana… - The Lancet, 2019 - thelancet.com
Background Oral immunotherapy is an emerging experimental treatment for peanut allergy,
but its benefits and harms are unclear. We systematically reviewed the efficacy and safety of …

Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study

RS Chinthrajah, N Purington, S Andorf, A Long… - The Lancet, 2019 - thelancet.com
Background Dietary avoidance is recommended for peanut allergies. We evaluated the
sustained effects of peanut allergy oral immunotherapy (OIT) in a randomised long-term …

EAACI Guidelines on allergen immunotherapy: IgE‐mediated food allergy

GB Pajno, M Fernandez‐Rivas, S Arasi, G Roberts… - Allergy, 2018 - Wiley Online Library
Food allergy can result in considerable morbidity, impairment of quality of life, and
healthcare expenditure. There is therefore interest in novel strategies for its treatment …

Food allergy across the globe

V Sampath, EM Abrams, B Adlou, C Akdis… - Journal of Allergy and …, 2021 - Elsevier
The prevalence of food allergy (FA) is increasing in some areas of the globe, highlighting the
need for better strategies for prevention, diagnosis, and therapy. In the last few decades, we …

Food allergy

H Renz, KJ Allen, SH Sicherer, HA Sampson… - Nature reviews Disease …, 2018 - nature.com
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin
and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic …

Allergen immunotherapy and/or biologicals for IgE‐mediated food allergy: a systematic review and meta‐analysis

D de Silva, P Rodríguez del Río, NW de Jong… - Allergy, 2022 - Wiley Online Library
Background There is substantial interest in immunotherapy and biologicals in IgE‐mediated
food allergy. Methods We searched six databases for randomized controlled trials about …

CSACI guidelines for the ethical, evidence-based and patient-oriented clinical practice of oral immunotherapy in IgE-mediated food allergy

P Bégin, ES Chan, H Kim, M Wagner… - Allergy, Asthma & …, 2020 - Springer
Background Oral immunotherapy (OIT) is an emerging approach to the treatment of patients
with IgE-mediated food allergy and is in the process of transitioning to clinical practice …