Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

S Alseekh, A Aharoni, Y Brotman, K Contrepois… - Nature …, 2021 - nature.com
Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However …

[HTML][HTML] NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

[HTML][HTML] The future of NMR-based metabolomics

JL Markley, R Brüschweiler, AS Edison… - Current opinion in …, 2017 - Elsevier
Highlights•NMR offers advantages for metabolomics that may be currently
underappreciated.•In future, NMR-based metabolomics needs to focus on its inherent …

[HTML][HTML] MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer

SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika… - Cancer cell, 2017 - cell.com
Poor response to cancer therapy due to resistance remains a clinical challenge. The present
study establishes a widely prevalent mechanism of resistance to gemcitabine in pancreatic …

[HTML][HTML] Analytical methods in untargeted metabolomics: state of the art in 2015

A Alonso, S Marsal, A Julià - Frontiers in bioengineering and …, 2015 - frontiersin.org
Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

Exploring the diversity of plant metabolism

C Fang, AR Fernie, J Luo - Trends in Plant Science, 2019 - cell.com
Plants produce a huge array of metabolites, far more than those produced by most other
organisms. Unraveling this diversity and its underlying genetic variation has attracted …

Metagenomics, metatranscriptomics, and metabolomics approaches for microbiome analysis: supplementary issue: bioinformatics methods and applications for big …

V Aguiar-Pulido, W Huang… - Evolutionary …, 2016 - journals.sagepub.com
Microbiomes are ubiquitous and are found in the ocean, the soil, and in/on other living
organisms. Changes in the microbiome can impact the health of the environmental niche in …

Metabolite measurement: pitfalls to avoid and practices to follow

W Lu, X Su, MS Klein, IA Lewis, O Fiehn… - Annual review of …, 2017 - annualreviews.org
Metabolites are the small biological molecules involved in energy conversion and
biosynthesis. Studying metabolism is inherently challenging due to metabolites' reactivity …

Multivariate analysis in metabolomics

B Worley, R Powers - Current metabolomics, 2013 - ingentaconnect.com
Metabolomics aims to provide a global snapshot of all small-molecule metabolites in cells
and biological fluids, free of observational biases inherent to more focused studies of …

Altered behavior, physiology, and metabolism in fish exposed to polystyrene nanoparticles

K Mattsson, MT Ekvall, LA Hansson… - … science & technology, 2015 - ACS Publications
The use of nanoparticles in consumer products, for example, cosmetics, sunscreens, and
electrical devices, has increased tremendously over the past decade despite insufficient …