Mechanochemical feedback loops in development and disease

E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Mechanochemical principles of spatial and temporal patterns in cells and tissues

A Bailles, EW Gehrels, T Lecuit - Annual review of cell and …, 2022 - annualreviews.org
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

Feather arrays are patterned by interacting signalling and cell density waves

WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley… - PLoS …, 2019 - journals.plos.org
Feathers are arranged in a precise pattern in avian skin. They first arise during development
in a row along the dorsal midline, with rows of new feather buds added sequentially in a …

Model systems for regeneration: Hydra

MC Vogg, B Galliot, CD Tsiairis - Development, 2019 - journals.biologists.com
The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …

Three-dimensional chiral morphodynamics of chemomechanical active shells

S Yin, B Li, XQ Feng - … of the National Academy of Sciences, 2022 - National Acad Sciences
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …

Roadmap for the multiscale coupling of biochemical and mechanical signals during development

PF Lenne, E Munro, I Heemskerk, A Warmflash… - Physical …, 2021 - iopscience.iop.org
The way in which interactions between mechanics and biochemistry lead to the emergence
of complex cell and tissue organization is an old question that has recently attracted …

Control of protein-based pattern formation via guiding cues

T Burkart, MC Wigbers, L Würthner, E Frey - Nature Reviews Physics, 2022 - nature.com
Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …

Mechanical patterning in animal morphogenesis

Y Maroudas-Sacks, K Keren - Annual Review of Cell and …, 2021 - annualreviews.org
Morphogenesis is one of the most remarkable examples of biological pattern formation.
Despite substantial progress in the field, we still do not understand the organizational …

Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback

D Menshykau, O Michos, C Lang, L Conrad… - Nature …, 2019 - nature.com
Branching patterns and regulatory networks differ between branched organs. It has
remained unclear whether a common regulatory mechanism exists and how organ-specific …

Pulsatile contractions and pattern formation in excitable actomyosin cortex

MF Staddon, EM Munro, S Banerjee - PLOS Computational …, 2022 - journals.plos.org
The actin cortex is an active adaptive material, embedded with complex regulatory networks
that can sense, generate, and transmit mechanical forces. The cortex exhibits a wide range …