Mechanochemical feedback loops in development and disease
E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …
roles in development and disease. The development of complex organisms, in particular …
Mechanochemical principles of spatial and temporal patterns in cells and tissues
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …
tissues, and embryos. Mathematical frameworks have been devised to account for the self …
Feather arrays are patterned by interacting signalling and cell density waves
WKW Ho, L Freem, D Zhao, KJ Painter, TE Woolley… - PLoS …, 2019 - journals.plos.org
Feathers are arranged in a precise pattern in avian skin. They first arise during development
in a row along the dorsal midline, with rows of new feather buds added sequentially in a …
in a row along the dorsal midline, with rows of new feather buds added sequentially in a …
Model systems for regeneration: Hydra
The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …
that promote wound healing, reactivation of a developmental process and, ultimately …
Three-dimensional chiral morphodynamics of chemomechanical active shells
Morphogenesis of active shells such as cells is a fundamental chemomechanical process
that often exhibits three-dimensional (3D) large deformations and chemical pattern …
that often exhibits three-dimensional (3D) large deformations and chemical pattern …
Roadmap for the multiscale coupling of biochemical and mechanical signals during development
The way in which interactions between mechanics and biochemistry lead to the emergence
of complex cell and tissue organization is an old question that has recently attracted …
of complex cell and tissue organization is an old question that has recently attracted …
Control of protein-based pattern formation via guiding cues
T Burkart, MC Wigbers, L Würthner, E Frey - Nature Reviews Physics, 2022 - nature.com
Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …
Reliable coordination of these functions requires the spatial and temporal organization of …
Mechanical patterning in animal morphogenesis
Y Maroudas-Sacks, K Keren - Annual Review of Cell and …, 2021 - annualreviews.org
Morphogenesis is one of the most remarkable examples of biological pattern formation.
Despite substantial progress in the field, we still do not understand the organizational …
Despite substantial progress in the field, we still do not understand the organizational …
Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback
D Menshykau, O Michos, C Lang, L Conrad… - Nature …, 2019 - nature.com
Branching patterns and regulatory networks differ between branched organs. It has
remained unclear whether a common regulatory mechanism exists and how organ-specific …
remained unclear whether a common regulatory mechanism exists and how organ-specific …
Pulsatile contractions and pattern formation in excitable actomyosin cortex
MF Staddon, EM Munro, S Banerjee - PLOS Computational …, 2022 - journals.plos.org
The actin cortex is an active adaptive material, embedded with complex regulatory networks
that can sense, generate, and transmit mechanical forces. The cortex exhibits a wide range …
that can sense, generate, and transmit mechanical forces. The cortex exhibits a wide range …