Biophysical Properties of Lumbricus terrestris Erythrocruorin and Its Potential Use as a Red Blood Cell Substitute

J Elmer, AF Palmer - Journal of functional biomaterials, 2012 - mdpi.com
Previous generations of hemoglobin (Hb)-based oxygen carriers (HBOCs) have been
plagued by key biophysical limitations that result in severe side-effects once transfused in …

[HTML][HTML] Direct comparison of oligochaete erythrocruorins as potential blood substitutes

D Zimmerman, M DiIusto, J Dienes… - Bioengineering & …, 2017 - ncbi.nlm.nih.gov
While many blood substitutes are based on mammalian hemoglobins (eg, human
hemoglobin, HbA), the naturally extracellular hemoglobins of invertebrates (aka …

Glutaraldehyde cross‐linking increases the stability of Lumbricus terrestris erythrocruorin

A Rajesh, D Zimmerman, K Spivack… - Biotechnology …, 2018 - Wiley Online Library
Since donated red blood cells must be constantly refrigerated, they are not available in
remote areas and battlefields. We have previously shown that the hemoglobin of the …

A spectroscopic study of uranyl-cytochrome b5/cytochrome c interactions

MH Sun, SQ Liu, KJ Du, CM Nie, YW Lin - Spectrochimica Acta Part A …, 2014 - Elsevier
Uranium is harmful to human health due to its radiation damage and the ability of uranyl ion
(UO 2 2+) to interact with various proteins and disturb their biological functions. Cytochrome …

Purification of Lumbricus terrestris erythrocruorin (LtEc) with anion exchange chromatography

B Timm, O Abdulmalik, A Chakrabarti… - Journal of Chromatography …, 2020 - Elsevier
The naturally extracellular hemoglobin (erythrocruorin) of the Canadian nightcrawler,
Lumbricus terrestris (LtEc), is a unique oxygen transport protein that may be an effective …

Initial biophysical characterization of Amynthas gracilis giant extracellular hemoglobin (HbAg)

JBS Oliveira, L Ramos, CO Souza, I Sebastião… - European Biophysics …, 2020 - Springer
The aim of the present work was the biophysical characterization of the Amynthas gracilis
hemoglobin (HbAg). The oxy-HbAg optical absorption data, with Soret and Q bands …

Guanidine hydrochloride and urea effects upon thermal stability of Glossoscolex paulistus hemoglobin (HbGp)

FAO Carvalho, FR Alves, JWP Carvalho… - International journal of …, 2015 - Elsevier
Glossoscolex paulistus hemoglobin (HbGp) has a molecular mass of 3600 kDa. It belongs to
the hexagonal bilayer hemoglobin class, which consists of highly cooperative respiratory …

Characteristics of hemoglobin and its pro‐oxidative activity in washed silver carp (Hypophthalmichthys molitrix) mince as affected by pH

M Javed, W Yu, H Yang, S Xiong… - Journal of Food …, 2021 - Wiley Online Library
The objectives of this study were to investigate the pro‐oxidative activity of hemoglobin and
its effect on lipid and protein oxidation changes in silver carp washed mince over 12 days of …

Metals content of Glossoscolex paulistus extracellular hemoglobin: Its peroxidase activity and the importance of these ions in the protein stability

CS Caruso, E Biazin, FAO Carvalho, M Tabak… - Journal of inorganic …, 2016 - Elsevier
In this work we investigate the presence of divalent cations bound to the Glossoscolex
paulistus (HbGp) hemoglobin and their effect over the protein stability and the peroxidase …

Characterization of the apo-form of extracellular hemoglobin of Glossoscolex paulistus (HbGp) and its stability in the presence of urea

AEB Barros, CS Caruso, FR Alves, M Tabak… - European Biophysics …, 2020 - Springer
The structural study of small heme-containing proteins, such as myoglobin, in the apo-form
lacking heme has been extensively described, but the characterization and stability of the …