Insights on cyclophosphamide metabolism and anticancer mechanism of action: A computational study

H Lakhmili, A Khadra, K Warda, A El-Abbassi… - Open …, 2024 - degruyter.com

Cyclophosphamide (CP) is a potent anticancer agent widely used to treat various
malignancies and autoimmune diseases after organ transplantation. However, its …

Spray-dried cyclophosphamide-loaded polyhydroxyalkanoate microparticles: design and characterization

S Lipaikin, A Dorokhin, G Ryltseva, A Oberenko… - ADMET and …, 2024 - pub.iapchem.org

Background and purpose: Cyclophosphamide (CP) is a widely used antitumor and
immunosuppressive drug, but it is highly cytotoxic and has carcinogenic and teratogenic …

[PDF] advetresearch.com

Pumpkin seed and grape seed extracts ameliorate cyclophosphamide-induced spermatogenesis inhibition in rat model: Histomorphometrical, immunohistochemical …

EM Samy, M Abd-Elraouf, ABI El-Mashad… - Journal of Advanced …, 2024 - advetresearch.com

This study investigated the protective efficacy of grape seed extract (GSE) and pumpkin
seed extract (PSE) against cyclophosphamide (CP)-induced testicular toxicity in adult male …

Investigating the Role of Obesity on Triple Negative Breast Cancer Progression and Development of Chemoresistance

HB de Mello Borges - 2024 - search.proquest.com

Breast cancer is the most common malignancy affecting women in the United States and
following lung cancer, it is the second leading cause of cancer-related death. Triple-negative …

[PDF] preprints.org

Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination With Anticancer Drugs on the c6 Rat Glioma Model

GK Mukusheva, RI Jalmakhanbetova, AZ Shaibek… - 2024 - preprints.org

Alkaloid-based urea derivatives were produced with high yield through the reaction of
anabasine and cytisine with isoxazolylphenylcarbamates in boiling benzene. Their …