The autosomal dominantly inherited disorder von Hippel–Lindau disease (VHL) is caused
by germline mutations in the VHL tumour suppressor gene (TSG). VHL mutations …

Summary von Hippel-Lindau disease is a heritable multisystem cancer syndrome that is
associated with a germline mutation of the VHL tumour suppressor gene on the short arm of …

Primary spinal cord tumors constitute 2% to 4% of all central nervous system neoplasms and
are characterized based on their location as intramedullary, intradural extramedullary, and …

Abstract von Hippel–Lindau (VHL) disease is an inheritable condition with an incidence of 1
in 36 000 live births. Individuals with VHL develop benign and malignant tumors including …

Object. The goals of this study were to define the natural history and growth pattern of
hemangioblastomas of the central nervous system (CNS) that are associated with von …

OBJECTIVE: To review a series of patients who underwent surgical removal of
intramedullary spinal cord tumors, focusing on the long-term functional outcome, recurrence …

Object With the introduction of electrophysiological spinal cord monitoring, surgeons have
been able to perform radical resection of intramedullary spinal cord tumors (IMSCTs) …

The management of patients with intradural spinal tumors differs in many respects from
approaches taken for patients with intracranial tumors. Intramedullary lesions are often …

Spinal cord tumors are uncommon neoplasms that, without treatment, can cause significant
neurologic morbidity and mortality. The historic classification of spine tumors is based on the …

Object Despite the frequency of cerebellar hemangioblastomas in von Hippel–Lindau (VHL)
disease, their optimum contemporary management has not been defined, and is made …