Recent advancements in mechanistic Research, therapeutic Potential, and Structure-Activity relationships of Aurora kinase inhibitors in cancer therapies
Aurora kinases (AURKs)—a family of serine/threonine protein kinases consisting of AURK-
A, AURK-B, and AURK-C, are critical regulators of chromosomal segregation, centrosome …
A, AURK-B, and AURK-C, are critical regulators of chromosomal segregation, centrosome …
Synthesis, biological screening, and binding mode analysis of some N-substituted tetrahydroquinoline analogs as apoptosis inducers and anticancer agents
One of the most common malignancies in the world is lung cancer. Lung cancer involves
mutations in many different genes, however, EGFR, KRAS, PTEN, and PIK3CA involvement …
mutations in many different genes, however, EGFR, KRAS, PTEN, and PIK3CA involvement …