Haemophilia A and B are hereditary haemorrhagic disorders characterised by deficiency or
dysfunction of coagulation protein factors VIII and IX, respectively. Recurrent joint and …

Systemic diseases of liver origin (SDLO) are complex diseases in multiple organ systems,
such as cardiovascular, musculoskeletal, endocrine, renal, respiratory, and sensory organ …

The classification of haemophilia originates from 1950s and has been adopted
unchallengedly by the ISTH in 2001. The aim of this study was: does the current …

Although high upfront costs for the high value of gene therapy have resulted in concerns
about sufficient reimbursement to allow patient access to these therapies, the significant …

Introduction Estimates of the size and characteristics of the US haemophilia population are
needed for healthcare planning and resource needs assessment. A network of …

Intracranial haemorrhage (ICH) is the most serious type of bleeding for patients with
haemophilia. Prior published reports regarding ICH predate the widespread provision of …

Aim To describe the prevalence and complications in babies≤ 2 years with haemophilia.
Methods We used a standardized collection tool to obtain consented data on eligible babies …

Intracranial haemorrhage (ICH) is the most serious event in haemophiliacs, resulting in high
rates of mortality and disability. Although the use of a prophylaxis regimen has improved …

Hemophilia A is characterized by deficiency in factor VIII clotting activity that results in
prolonged oozing after injuries, tooth extractions, or surgery, and delayed or recurrent …

Severe and moderate factor VIII (FVIII) or IX (FIX) deficiencies in female carriers of
haemophilia are rarely observed, but mild deficiency is quite frequent, although insufficiently …